Viruses in the family Filoviridae, including the commonly known Ebola (EBOV) and Marburg
(MARV) viruses, can cause severe hemorrhagic fever in humans and nonhuman primates …

Ebola virus (EBOV) causes epidemics with high mortality yet remains understudied due to
the challenge of experimentation in high-containment and outbreak settings. Here, we used …

This fifth edition volume expands on the previous editions by presenting readers with the
latest developments and emerging methodologies in cytometry. The chapters in this book …

Non-human primate (NHP) animal models are an integral part of the drug research and
development process. For some biothreat pathogens, animal model challenge studies may …

World Health Organization (WHO) Risk Group-4 (RG-4) pathogens are among the most
dangerous of the emergent and re-emergent viruses. International health agencies, working …

The emergence of new pathogens continues to fuel the need for advanced high-
containment laboratories across the globe. Here we explore challenges and opportunities …

High-consequence pathogens such as the Ebola, Marburg, and Lassa viruses are handled
in maximum-containment biosafety level 4 (BSL-4) laboratories. Genetic material is often …

This chapter attempts to encompass and tackle a large problem in Astrovirology and
Astrobiology. There is a huge anthropomorphic prejudice that although life is unlikely, the …