The MYC proto-oncogenes encode a family of transcription factors that are among the most
commonly activated oncoproteins in human neoplasias. Indeed, MYC aberrations or …

MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …

In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …

MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that function in regulation of
gene expression. Compelling evidences have demonstrated that miRNA expression is …

Altered gene expression is the primary molecular mechanism responsible for the
pathological processes of human diseases, including cancer. MicroRNAs (miRNAs) are …

MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …

The MYC oncogene contributes to the genesis of many human cancers. Recent insights into
its expression and function have led to therapeutic opportunities. MYC's activation by …

MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …

The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …

MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …