Positron emission tomography (PET) and single-photon emission computed tomography
(SPECT) are molecular imaging strategies that typically use radioactively labeled ligands to …

Nanomedicine approaches can effectively modulate the biodistribution and bioavailability of
therapeutic agents, improving their therapeutic index. However, despite the ever-increasing …

Portable gamma cameras suitable for intraoperative imaging are in active development and
testing. These cameras utilise a range of collimation, detection, and readout architectures …

Molecular radiotherapy using 177Lu-DOTATATE is a most effective treatment for
somatostatin receptor–expressing neuroendocrine tumors. Despite its frequent and …

Bone sarcomas are devastating primary bone cancers that mostly affect children, young
adults, and the elderly. These aggressive tumors are associated with poor survival, and …

Background In spite of the tremendous potential of game‐changing biological image‐and/or
biologically guided radiation therapy (RT) and adaptive radiation therapy for cancer …

Despite improvements in small animal PET instruments, many tracers cannot be imaged at
sufficiently high resolutions due to positron range, while multi-tracer PET is hampered by the …

Purpose CXCR3 is expressed on activated T cells and plays a crucial role in T-cell
recruitment to the tumor microenvironment (TME) during cell-based and immune checkpoint …

Compton cameras can offer advantages over gamma cameras for some applications, since
they are well suited for multitracer imaging and for imaging high-energy radiotracers, such …

Immuno-oncological treatment strategies that target abnormal receptor profiles of tumors are
an increasingly important feature of cancer therapy. Yet, assessing receptor availability (RA) …