Myeloperoxidase (MPO) belongs to the family of heme-containing peroxidases, produced
mostly from polymorphonuclear neutrophils. The active enzyme (150 kDa) is the product of …

Significance: Myeloperoxidase (MPO) is a heme peroxidase that is primarily expressed by
neutrophils. It has the capacity to generate several reactive species, essential for its inherent …

During their lifespan, red blood cells (RBCs) are exposed to a large number of stressors and
are therefore considered as a suitable model to investigate cell response to oxidative stress …

Cardiovascular diseases and oxidative stress are related to polycystic ovary syndrome
(PCOS) and insulin resistance (IR). We have evaluated the relationship between …

Arterial cardiovascular events are the leading cause of death in patients with JAK2V617F
myeloproliferative neoplasms (MPNs). However, their mechanisms are poorly understood …

Hypochlorous acid (HOCl), one of the major precursors of free radicals in body cells and
tissues, is endowed with strong prooxidant activity. In living systems, dinitrosyl iron …

Phosphatidylserine (PS) exposure increases as red cells age, and is an important signal for
the removal of senescent cells from the circulation. PS exposure is elevated in red cells from …

Myeloperoxidase (MPO) is an oxidant-producing enzyme that can also regulate cellular
functions via its nonenzymatic effects. Mature active MPO isolated from normal human …

Myeloperoxidase (MPO) is one of the most abundantly expressed proteins in neutrophils. It
serves as a critical component of the antimicrobial defense system, facilitating microbial …

High-fat meal (HFM) consumption can produce acute lipemia and trigger myocardial
infarction in patients with atherosclerosis, but the mechanisms are poorly understood …