Engineered hydrogels for mechanobiology

U Blache, EM Ford, B Ha, L Rijns… - Nature Reviews …, 2022 - nature.com
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

Towards organoid culture without Matrigel

MT Kozlowski, CJ Crook, HT Ku - Communications biology, 2021 - nature.com
Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …

Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions

J Liu, YS Huang, Y Liu, D Zhang, K Koynov, HJ Butt… - Nature Chemistry, 2024 - nature.com
Stimuli-responsive hydrogels with programmable shape changes are promising materials
for soft robots, four-dimensional printing, biomedical devices and artificial intelligence …

Three-dimensional nanofabrication via ultrafast laser patterning and kinetically regulated material assembly

F Han, S Gu, A Klimas, N Zhao, Y Zhao, SC Chen - Science, 2022 - science.org
A major challenge in nanotechnology is the fabrication of complex three-dimensional (3D)
structures with desired materials. We present a strategy for fabricating arbitrary 3D …

Photopolymerizable biomaterials and light-based 3D printing strategies for biomedical applications

C Yu, J Schimelman, P Wang, KL Miller, X Ma… - Chemical …, 2020 - ACS Publications
Since the advent of additive manufacturing, known commonly as 3D printing, this technology
has revolutionized the biofabrication landscape and driven numerous pivotal advancements …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Design challenges in polymeric scaffolds for tissue engineering

MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Visible-light-mediated modification and manipulation of biomacromolecules

VM Lechner, M Nappi, PJ Deneny, S Folliet… - Chemical …, 2021 - ACS Publications
Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …

Stimuli-responsive hydrogels: the dynamic smart biomaterials of tomorrow

M Neumann, G di Marco, D Iudin, M Viola… - …, 2023 - ACS Publications
In the past decade, stimuli-responsive hydrogels are increasingly studied as biomaterials for
tissue engineering and regenerative medicine purposes. Smart hydrogels can not only …