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Engineered hydrogels for mechanobiology
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
Towards organoid culture without Matrigel
Organoids—cellular aggregates derived from stem or progenitor cells that recapitulate organ
function in miniature—are of growing interest in developmental biology and medicine …
function in miniature—are of growing interest in developmental biology and medicine …
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions
Stimuli-responsive hydrogels with programmable shape changes are promising materials
for soft robots, four-dimensional printing, biomedical devices and artificial intelligence …
for soft robots, four-dimensional printing, biomedical devices and artificial intelligence …
Three-dimensional nanofabrication via ultrafast laser patterning and kinetically regulated material assembly
A major challenge in nanotechnology is the fabrication of complex three-dimensional (3D)
structures with desired materials. We present a strategy for fabricating arbitrary 3D …
structures with desired materials. We present a strategy for fabricating arbitrary 3D …
Photopolymerizable biomaterials and light-based 3D printing strategies for biomedical applications
Since the advent of additive manufacturing, known commonly as 3D printing, this technology
has revolutionized the biofabrication landscape and driven numerous pivotal advancements …
has revolutionized the biofabrication landscape and driven numerous pivotal advancements …
3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …
Design challenges in polymeric scaffolds for tissue engineering
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …
Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …
Visible-light-mediated modification and manipulation of biomacromolecules
Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …
have become crucial tools in chemical biology. They are extensively used not only to …
Stimuli-responsive hydrogels: the dynamic smart biomaterials of tomorrow
In the past decade, stimuli-responsive hydrogels are increasingly studied as biomaterials for
tissue engineering and regenerative medicine purposes. Smart hydrogels can not only …
tissue engineering and regenerative medicine purposes. Smart hydrogels can not only …