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[HTML][HTML] What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
has caused more than 1 million deaths in the first 6 months of the pandemic and huge …
Convergent evolution in SARS-CoV-2 spike creates a variant soup from which new COVID-19 waves emerge
The first 2 years of the COVID-19 pandemic were mainly characterized by recurrent
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …
mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 and P681 …
COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P. 1 emergence
The northern state of Amazonas is among the regions in Brazil most heavily affected by the
COVID-19 epidemic and has experienced two exponentially growing waves, in early and …
COVID-19 epidemic and has experienced two exponentially growing waves, in early and …
[HTML][HTML] LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
K Westendorf, S Žentelis, L Wang, D Foster… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
[HTML][HTML] Genomic evidence for reinfection with SARS-CoV-2: a case study
Background The degree of protective immunity conferred by infection with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the …
[HTML][HTML] The SARS-CoV-2 mutations versus vaccine effectiveness: New opportunities to new challenges
JA Malik, S Ahmed, A Mir, M Shinde, O Bender… - Journal of infection and …, 2022 - Elsevier
Abstract Background The SARS-CoV-2 coronavirus epidemic is hastening the discovery of
the most efficient vaccines. The development of cost-effective vaccines seems to be the only …
the most efficient vaccines. The development of cost-effective vaccines seems to be the only …
[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …
Wuhan to world: the COVID-19 pandemic
COVID-19 is a Severe Acute Respiratory Syndrome (SARS), caused by SARS-CoV-2, a
novel virus which belongs to the family Coronaviridae. It was first reported in December …
novel virus which belongs to the family Coronaviridae. It was first reported in December …
[HTML][HTML] D614G spike mutation increases SARS CoV-2 susceptibility to neutralization
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein acquired
a D614G mutation early in the pandemic that confers greater infectivity and is now the …
a D614G mutation early in the pandemic that confers greater infectivity and is now the …
SARS-CoV-2 mutations and their viral variants
Mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occur
spontaneously during replication. Thousands of mutations have accumulated and continue …
spontaneously during replication. Thousands of mutations have accumulated and continue …