Enzyme Inhibition in Managing Cardiovascular Diseases

S Kumar, S Saha, A Babu, M Agrawal… - Current Enzyme …, 2024 - benthamdirect.com
Enzyme inhibition stands as a crucial strategy in tackling cardiovascular diseases (CVDs),
countering their significant global impact on health. Targeting key enzymes involved in …

Simulation of drug-drug interactions between breast cancer chemotherapeutic agents and antiemetic drugs

S Deb, R Hopefl - DARU Journal of Pharmaceutical Sciences, 2023 - Springer
Background Chemotherapy-induced nausea and vomiting are commonly experienced side
effects in breast cancer (BCa) patients. Antiemetic drugs used in BCa treatment are either …

Pharmacological Strategies for Enzyme Inhibition in Disease Therapeutics: A Comprehensive Review

G Verma, B Bhushan, G Singh, K Singh… - Current Enzyme …, 2024 - ingentaconnect.com
Enzyme inhibition is a crucial pharmacological approach for treating various diseases as it
targets enzymes involved in disease pathogenesis. This review explores the fundamental …

The Impact of Hemp Seed Oil on Drug-Drug Interactions: A Comprehensive Review of Potential Mechanisms and Clinical Implications

S Solaimanian, B Rahmani, MR Shiri-Shahsavar - 2023 - researchsquare.com
Hemp seed oil (HSO), esteemed for its potential health benefits and therapeutic attributes,
has garnered substantial attention in recent years. However, the escalating consumption of …

Inhibition of Cytochrome P450s by Strobilanthes crispus Sub-Fraction (F3): Implication for Herb–Drug Interaction

YF Yong, MWO Liew, NS Yaacob - European Journal of Drug Metabolism …, 2022 - Springer
Abstract Background and Objective Strobilanthes crispus Blume sub-fraction (F3) has been
reported to be cytotoxic against cancer cells and to cause murine mammary tumor …

Medical cannabis: Roles, responsibilities, and challenges for clinical pharmacists

L Sera, N Duncan - Journal of the American College of Clinical …, 2023 - Wiley Online Library
Cannabis is a plant that has been grown for centuries for it is industrial, medicinal, and
recreational uses. Over the last few decades, cannabis has been increasingly used …

Development and Application of Cytochrome P450 CYP3A7 Inhibition Models to Assess Drug Safety in Fetuses and Neonates

HM Work - 2024 - search.proquest.com
Cytochrome P450s (CYPs) are abundantly expressed in human livers and act as
detoxification enzymes by metabolizing many pharmacological agents and environmental …

[PDF][PDF] Exploration of Secondary Metabolites in Flower-Petal Annona muricata as Agonists for Peroxisome Proliferator-Activated Receptor-Alpha (PPARα) for Liver …

S Ololade Zacchaeus, L Labunmi, F Onifade Olayinka… - 2023 - phytopharmajournal.com
The expression of PPARα in the liver is significantly increased in both non-alcoholic fatty
liver disease (NAFLD) patients and experimental models. Animal studies have shown …

[BOOK][B] Elucidating the Causal Mechanisms of Alzheimer's Disease Using Cell-Based Models

V Narayanan - 2022 - search.proquest.com
The lack of a preventive therapy for neurodegenerative diseases, such as Alzheimer's
Disease (AD) has increased the urgency for gaining an understanding of the mechanisms …

[CITATION][C] Pretest self-assessment question

A Escitalopram, B Sertraline, C Fluvoxamine…