Enzymatic processing of lignocellulosic biomass: principles, recent advances and perspectives

H Østby, LD Hansen, SJ Horn… - Journal of Industrial …, 2020 - academic.oup.com
Efficient saccharification of lignocellulosic biomass requires concerted development of a
pretreatment method, an enzyme cocktail and an enzymatic process, all of which are …

Oxidoreductases and reactive oxygen species in conversion of lignocellulosic biomass

B Bissaro, A Várnai, ÅK Røhr… - … and Molecular Biology …, 2018 - Am Soc Microbiol
Biomass constitutes an appealing alternative to fossil resources for the production of
materials and energy. The abundance and attractiveness of vegetal biomass come along …

Structural diversity of lytic polysaccharide monooxygenases

G Vaaje-Kolstad, Z Forsberg, JSM Loose… - Current opinion in …, 2017 - Elsevier
Highlights•LPMOs show large structural and sequence variability that affect substrate-
interaction surfaces.•First X-ray crystallographic data on cellulose binding.•Large modular …

Oxygen activation by Cu LPMOs in recalcitrant carbohydrate polysaccharide conversion to monomer sugars

KK Meier, SM Jones, T Kaper, H Hansson… - Chemical …, 2017 - ACS Publications
Natural carbohydrate polymers such as starch, cellulose, and chitin provide renewable
alternatives to fossil fuels as a source for fuels and materials. As such, there is considerable …

Environmental temperature alters the digestive performance and gut microbiota of a terrestrial amphibian

SS Fontaine, AJ Novarro… - Journal of Experimental …, 2018 - journals.biologists.com
Environmental temperature and gut microbial communities can both have profound impacts
on the digestive performance of ectothermic vertebrates. Additionally, the diversity …

On the impact of carbohydrate-binding modules (CBMs) in lytic polysaccharide monooxygenases (LPMOs)

Z Forsberg, G Courtade - Essays in Biochemistry, 2023 - portlandpress.com
Lytic polysaccharide monooxygenases (LPMOs) have revolutionized our understanding of
how enzymes degrade insoluble polysaccharides. Compared with the substantial …

The carbohydrate-binding module and linker of a modular lytic polysaccharide monooxygenase promote localized cellulose oxidation

G Courtade, Z Forsberg, EB Heggset… - Journal of Biological …, 2018 - ASBMB
Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent enzymes that
catalyze the oxidative cleavage of polysaccharides such as cellulose and chitin, a feature …

Methylation of the N‐terminal histidine protects a lytic polysaccharide monooxygenase from auto‐oxidative inactivation

DM Petrović, B Bissaro, P Chylenski… - Protein …, 2018 - Wiley Online Library
The catalytically crucial N‐terminal histidine (His1) of fungal lytic polysaccharide
monooxygenases (LPMOs) is post‐translationally modified to carry a methylation. The …

Addressing challenges in production of cellulases for biomass hydrolysis: Targeted interventions into the genetics of cellulase producing fungi

RK Sukumaran, M Christopher, P Kooloth-Valappil… - Bioresource …, 2021 - Elsevier
Lignocellulosic materials are the favoured feedstock for biorefineries due to their abundant
availability and non-completion with food. Biobased technologies for refining these materials …

A lytic polysaccharide monooxygenase-like protein functions in fungal copper import and meningitis

S Garcia-Santamarina, C Probst, RA Festa… - Nature Chemical …, 2020 - nature.com
Infection by the fungal pathogen Cryptococcus neoformans causes lethal meningitis,
primarily in immune-compromised individuals. Colonization of the brain by C. neoformans is …