Recent application of Raman spectroscopy in tumor diagnosis: from conventional methods to artificial intelligence fusion

Y Qi, Y Liu, J Luo - PhotoniX, 2023 - Springer
Raman spectroscopy, as a label-free optical technology, has widely applied in tumor
diagnosis. Relying on the different Raman technologies, conventional diagnostic methods …

The complementary value of intraoperative fluorescence imaging and Raman spectroscopy for cancer surgery: combining the incompatibles

LJ Lauwerends, H Abbasi, TC Bakker Schut… - European Journal of …, 2022 - Springer
A clear margin is an important prognostic factor for most solid tumours treated by surgery.
Intraoperative fluorescence imaging using exogenous tumour-specific fluorescent agents …

Selective-sampling Raman imaging techniques for ex vivo assessment of surgical margins in cancer surgery

MG Lizio, R Boitor, I Notingher - Analyst, 2021 - pubs.rsc.org
One of the main challenges in cancer surgery is to ensure the complete excision of the
tumour while sparing as much healthy tissue as possible. Histopathology, the gold-standard …

Diagnostic accuracy of autofluorescence-Raman microspectroscopy for surgical margin assessment during Mohs micrographic surgery of basal cell carcinoma

RA Boitor, S Varma, A Sharma, S Odedra… - British Journal of …, 2024 - academic.oup.com
Abstract Background Autofluorescence (AF)–Raman microspectroscopy is a technology that
can detect residual basal cell carcinoma (BCC) on the resection margin of fresh, surgically …

[HTML][HTML] Emerging minimally invasive technologies for the detection of skin cancer

JM Jung, JY Cho, WJ Lee, SE Chang, MW Lee… - Journal of personalized …, 2021 - mdpi.com
With the increasing incidence of skin cancer, many noninvasive technologies to detect its
presence have been developed. This review focuses on reflectance confocal microscopy …

Intra-operative assessment of sentinel lymph nodes for breast cancer surgery: an update

S Barkur, I Notingher, E Rakha - Surgical Oncology, 2022 - Elsevier
Lymph node (LN) involvement is the strongest prognostic factor in operable breast cancer
(BC). Therefore, accurate assessment of LN status is essential for management of BC …

[HTML][HTML] Autofluorescence-Raman Spectroscopy for Ex vivo map** colorectal liver metastases and liver tissue

C Corden, R Boitor, PK Dusanjh, A Harwood… - journal of surgical …, 2023 - Elsevier
Introduction Identifying colorectal liver metastases (CRLM) during liver resection could assist
in achieving clear surgical margins, which is an important prognostic variable for both …

[HTML][HTML] Application of the OSNA Technique (One-Step Nucleic Acid Amplification Test) in Breast Cancer

G Sychowski, H Romanowicz, B Smolarz - International Journal of …, 2025 - mdpi.com
Breast cancer is one of the most common cancers diagnosed in both countries with high and
low levels of socio-academic development. Routine, regular screening tests being …

Time-gated Raman spectroscopy for biomedical application under ambient or strong background light conditions

C Corden, R Boitor, I Notingher - Journal of Physics D: Applied …, 2021 - iopscience.iop.org
Many biomedical applications require measurements of Raman spectra of tissue under
ambient lighting conditions. However, the background light often swamps the weaker …

Raman Spectroscopy for Colorectal Tumor Margin Assessment: A Promising Tool for Real-Time Surgical Delimitation.

M Karnachoriti, MA Kouri, E Spyratou, N Danias… - Talanta, 2025 - Elsevier
Raman spectroscopy is a promising non-invasive technique not only for the rapid and
accurate detection of colorectal cancer (CRC) but also for the identification of positive …