B cells, antibodies, and more

W Hoffman, FG Lakkis, G Chalasani - Clinical Journal of the …, 2016 - journals.lww.com
B cells play a central role in the immunopathogenesis of glomerulonephritides and
transplant rejection. B cells secrete antibodies that contribute to tissue injury via multiple …

B10 cells: a functionally defined regulatory B cell subset

TF Tedder - The Journal of Immunology, 2015 - journals.aai.org
B cells are commonly thought to enhance inflammatory immune responses. However,
specific regulatory B cell subsets recently were identified that downregulate adaptive and …

Effector mechanisms of rejection

A Moreau, E Varey, I Anegon… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Organ transplantation appears today to be the best alternative to replace the loss of vital
organs induced by various diseases. Transplants can, however, also be rejected by the …

B10 cell regulation of health and disease

KM Candando, JM Lykken, TF Tedder - Immunological reviews, 2014 - Wiley Online Library
While B cells are traditionally regarded as promoters of the immune response via antibody
secretion and pro‐inflammatory cytokine production, recent studies have also confirmed an …

Regulatory B cells: the cutting edge of immune tolerance in kidney transplantation

B Peng, Y Ming, C Yang - Cell death & disease, 2018 - nature.com
Kidney transplantation is the optimal treatment for end-stage renal diseases. Although great
improvement has been achieved, immune tolerance is still the Holy Grail that every organ …

Immunological challenges associated with artificial skin grafts: available solutions and stem cells in future design of synthetic skin

S Dixit, DR Baganizi, R Sahu, E Dosunmu… - Journal of biological …, 2017 - Springer
The repair or replacement of damaged skins is still an important, challenging public health
problem. Immune acceptance and long-term survival of skin grafts represent the major …

[HTML][HTML] Targeting B cells and antibody in transplantation

MR Clatworthy - American journal of transplantation, 2011 - Elsevier
There has been increasing interest in the role played by B cells, plasma cells and their
associated antibody in the immune response to an allograft, driven by the need to undertake …

B cells in transplant tolerance and rejection: friends or foes?

R Schmitz, ZW Fitch, PM Schroder… - Transplant …, 2020 - Wiley Online Library
Our understanding of the role of B cells in organ transplantation remains incomplete and
continues to grow. The majority of research has focused on the detrimental role of antibodies …

Safety of CAR T-cell therapy in kidney transplant recipients

O Mamlouk, R Nair, SP Iyer, A Edwards… - Blood, The Journal …, 2021 - ashpublications.org
COI notes: SI: Research Grant and Consultant-Seattle Genetics, Rhizen, Daiichi Sankyo,
Trillium; Research Grant-Merck, Affimed, Spectrum. SSN served as Advisory Board member …

Regulatory B cells

L Wang, Y Fu, Y Chu - B Cells in Immunity and Tolerance, 2020 - Springer
B cells are typically characterized by their ability to produce antibodies, function as
secondary antigen-present cells, and produce various immunoregulatory cytokines. The …