Tumor development and metastasis are closely related to the tumor microenvironment
(TME). Recently, several studies indicate that modulating TME can enhance cancer …

Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low
acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …

Hypoxia increases patient treatment resistance and favors cancer progression. Nanozymes
have received unprecedented attention in alleviating hypoxia via catalase (CAT)-mimicking …

This research proposes the one-pot preparation of polydopamine (PDA) decorated
mesoporous silica nanoparticle (PMSN) for the thermal and tumor micro-environment (TME) …

The activable NIR-based phototheranostic nanoplatform (NP) is considered an efficient and
reliable tumor treatment due to its strong targeting ability, flexible controllability, minimal side …

Metal-organic frameworks (MOFs) have been developed for tumor therapy in recent years,
but so far there have been very few reports about the use of single metallic manganese (Mn) …

Chemodynamic therapy (CDT), as an emerging therapeutic strategy, kills cancer cells by
converting intracellular hydrogen peroxide (H 2 O 2) into cytotoxic oxidizing hydroxyl …

Ferroptosis is a type of regulated cell death that has attracted much attention owing to its
ability to trigger immunogenic cell death (ICD) and enhance immunotherapy. However …

Ferroptosis has garnered considerable attention benefiting from its remarkable potential in
fighting malignant tumors. Its occurrence largely relies the overwhelming accumulation of …

Killing tumor cells through apoptosis and/or ferroptosis pathways has been extensively
explored for tumor therapy. However, the therapeutic efficacy is always impaired by the …