The intestinal barrier in disorders of the central nervous system

C Pellegrini, M Fornai, V D'Antongiovanni… - The lancet …, 2023 - thelancet.com
The intestinal barrier, which primarily consists of a mucus layer, an epithelial barrier, and a
gut vascular barrier, has a crucial role in health and disease by facilitating nutrient …

Changes in gut microbiota and multiple sclerosis: a systematic review

A Ordoñez-Rodriguez, P Roman… - International Journal of …, 2023 - mdpi.com
Introduction: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease
mediated by autoimmune reactions against myelin proteins and gangliosides in the grey …

Gut dysbiosis and fecal microbiota transplantation in autoimmune diseases

P Belvoncikova, M Maronek, R Gardlik - International journal of molecular …, 2022 - mdpi.com
Gut microbiota dysbiosis has recently been reported in a number of clinical states, including
neurological, psychiatric, cardiovascular, metabolic and autoimmune disorders. Yet, it is not …

Role of Akkermansia in Human Diseases: From Causation to Therapeutic Properties

A Pellegrino, G Coppola, F Santopaolo, A Gasbarrini… - Nutrients, 2023 - mdpi.com
The gut microbiota plays a critical role in the modulation of host metabolism and immune
response, and its impairment has been implicated in many gastrointestinal and …

Dietary Fat Modulation of Gut Microbiota and Impact on Regulatory Pathways Controlling Food Intake

S Hamamah, A Amin, AL Al-Kassir, J Chuang… - Nutrients, 2023 - mdpi.com
Obesity is a multifactorial disease that continues to increase in prevalence worldwide.
Emerging evidence has shown that the development of obesity may be influenced by …

Food, gut barrier dysfunction, and related diseases: A new target for future individualized disease prevention and management

L Liang, C Saunders, N Sanossian - Food Science & Nutrition, 2023 - Wiley Online Library
Dysfunction of gut barrier is known as “leaky gut” or increased intestinal permeability.
Numerous recent scientific evidences showed the association between gut dysfunction and …

Zonulin as a Biomarker for the Development of Celiac Disease

TM DaFonte, F Valitutti, V Kenyon, JJ Locascio… - …, 2024 - publications.aap.org
OBJECTIVES Increased intestinal permeability seems to be a key factor in the pathogenesis
of autoimmune diseases, including celiac disease (CeD). However, it is unknown whether …

Identification of commensal gut microbiota signatures as predictors of clinical severity and disease progression in multiple sclerosis

TL Montgomery, Q Wang, A Mirza, D Dwyer, Q Wu… - Scientific Reports, 2024 - nature.com
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system and a
leading cause of neurological disability in young adults. Clinical presentation and disease …

The second brain: The connection between gut microbiota composition and multiple sclerosis

M Farshbafnadi, E Agah, N Rezaei - Journal of neuroimmunology, 2021 - Elsevier
Gut microbiota composition may affect the central nervous system (CNS) and immune
function. Several studies have recently examined the possible link between gut microbiota …

Mediterranean diet and associations with the gut microbiota and pediatric-onset multiple sclerosis using trivariate analysis

AI Mirza, F Zhu, N Knox, LJ Black, A Daly… - Communications …, 2024 - nature.com
Background The interplay between diet and the gut microbiota in multiple sclerosis (MS) is
poorly understood. We aimed to assess the interrelationship between diet, the gut …