Enzymatic reductions for the chemist

F Hollmann, IWCE Arends, D Holtmann - Green Chemistry, 2011 - pubs.rsc.org
When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

Reduction of polynitroaromatic compounds: the bacterial nitroreductases

MD Roldán, E Pérez-Reinado, F Castillo… - FEMS microbiology …, 2008 - academic.oup.com
Most nitroaromatic compounds are toxic and mutagenic for living organisms, but some
microorganisms have developed oxidative or reductive pathways to degrade or transform …

Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases

HS Toogood, JM Gardiner, NS Scrutton - ChemCatChem, 2010 - Wiley Online Library
The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts
with major applications in the industrial reduction of activated alkenes. These enzymes have …

Asymmetric bioreduction of activated C= C bonds using enoate reductases from the old yellow enzyme family

R Stuermer, B Hauer, M Hall, K Faber - Current opinion in chemical biology, 2007 - Elsevier
The asymmetric bioreduction of alkenes bearing an electron-withdrawing group using flavin-
dependent enzymes from the 'old yellow enzyme'family at the expense of NAD (P) H yields …

[HTML][HTML] Biotransformation and degradation of 2, 4, 6-trinitrotoluene by microbial metabolism and their interaction

MY Serrano-González, R Chandra… - Defence technology, 2018 - Elsevier
Abstract 2, 4, 6-trinitrotoluene (TNT) and its derivatives are nitrogen-containing aromatic
compounds having chemical and thermal stability at ambient temperature and pressure …

Biocatalytic reductions: from lab curiosity to “first choice”

SMA De Wildeman, T Sonke… - Accounts of Chemical …, 2007 - ACS Publications
Enzyme-catalyzed reductions have been studied for decades and have been introduced in
more than 10 industrial processes for production of various chiral alcohols, α-hydroxy acids …

[HTML][HTML] Asymmetric bioreduction of activated alkenes to industrially relevant optically active compounds

CK Winkler, G Tasnádi, D Clay, M Hall, K Faber - Journal of biotechnology, 2012 - Elsevier
Ene-reductases from the 'Old Yellow Enzyme'family of flavoproteins catalyze the asymmetric
reduction of various α, β-unsaturated compounds at the expense of a nicotinamide cofactor …

Electrochemical Sensor for Detecting Ultratrace Nitroaromatic Compounds Using Mesoporous SiO2-Modified Electrode

HX Zhang, AM Cao, JS Hu, LJ Wan, ST Lee - Analytical chemistry, 2006 - ACS Publications
An electrochemical sensor for ultratrace nitroaromatic compounds (NACs) using
mesoporous SiO2 of MCM-41 as sensitive materials is reported. MCM-41 was synthesized …

Old yellow enzyme-catalysed asymmetric hydrogenation: linking family roots with improved catalysis

A Scholtissek, D Tischler, AH Westphal… - Catalysts, 2017 - mdpi.com
Asymmetric hydrogenation of activated alkenes catalysed by ene-reductases from the old
yellow enzyme family (OYEs) leading to chiral products is of potential interest for industrial …

Spread, behavior, and ecosystem consequences of conventional munitions compounds in coastal marine waters

AJ Beck, M Gledhill, C Schlosser, B Stamer… - Frontiers in Marine …, 2018 - frontiersin.org
Coastal marine environments are contaminated globally with a vast quantity of unexploded
ordnance and munitions from intentional disposal. These munitions contain organic …