Enzymatic reductions for the chemist
When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …
Reduction of polynitroaromatic compounds: the bacterial nitroreductases
MD Roldán, E Pérez-Reinado, F Castillo… - FEMS microbiology …, 2008 - academic.oup.com
Most nitroaromatic compounds are toxic and mutagenic for living organisms, but some
microorganisms have developed oxidative or reductive pathways to degrade or transform …
microorganisms have developed oxidative or reductive pathways to degrade or transform …
Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases
The old yellow enzyme (OYE) family is a large group of flavin‐dependent redox biocatalysts
with major applications in the industrial reduction of activated alkenes. These enzymes have …
with major applications in the industrial reduction of activated alkenes. These enzymes have …
Asymmetric bioreduction of activated C= C bonds using enoate reductases from the old yellow enzyme family
R Stuermer, B Hauer, M Hall, K Faber - Current opinion in chemical biology, 2007 - Elsevier
The asymmetric bioreduction of alkenes bearing an electron-withdrawing group using flavin-
dependent enzymes from the 'old yellow enzyme'family at the expense of NAD (P) H yields …
dependent enzymes from the 'old yellow enzyme'family at the expense of NAD (P) H yields …
[HTML][HTML] Biotransformation and degradation of 2, 4, 6-trinitrotoluene by microbial metabolism and their interaction
MY Serrano-González, R Chandra… - Defence technology, 2018 - Elsevier
Abstract 2, 4, 6-trinitrotoluene (TNT) and its derivatives are nitrogen-containing aromatic
compounds having chemical and thermal stability at ambient temperature and pressure …
compounds having chemical and thermal stability at ambient temperature and pressure …
Biocatalytic reductions: from lab curiosity to “first choice”
SMA De Wildeman, T Sonke… - Accounts of Chemical …, 2007 - ACS Publications
Enzyme-catalyzed reductions have been studied for decades and have been introduced in
more than 10 industrial processes for production of various chiral alcohols, α-hydroxy acids …
more than 10 industrial processes for production of various chiral alcohols, α-hydroxy acids …
[HTML][HTML] Asymmetric bioreduction of activated alkenes to industrially relevant optically active compounds
Ene-reductases from the 'Old Yellow Enzyme'family of flavoproteins catalyze the asymmetric
reduction of various α, β-unsaturated compounds at the expense of a nicotinamide cofactor …
reduction of various α, β-unsaturated compounds at the expense of a nicotinamide cofactor …
Electrochemical Sensor for Detecting Ultratrace Nitroaromatic Compounds Using Mesoporous SiO2-Modified Electrode
HX Zhang, AM Cao, JS Hu, LJ Wan, ST Lee - Analytical chemistry, 2006 - ACS Publications
An electrochemical sensor for ultratrace nitroaromatic compounds (NACs) using
mesoporous SiO2 of MCM-41 as sensitive materials is reported. MCM-41 was synthesized …
mesoporous SiO2 of MCM-41 as sensitive materials is reported. MCM-41 was synthesized …
Old yellow enzyme-catalysed asymmetric hydrogenation: linking family roots with improved catalysis
A Scholtissek, D Tischler, AH Westphal… - Catalysts, 2017 - mdpi.com
Asymmetric hydrogenation of activated alkenes catalysed by ene-reductases from the old
yellow enzyme family (OYEs) leading to chiral products is of potential interest for industrial …
yellow enzyme family (OYEs) leading to chiral products is of potential interest for industrial …
Spread, behavior, and ecosystem consequences of conventional munitions compounds in coastal marine waters
Coastal marine environments are contaminated globally with a vast quantity of unexploded
ordnance and munitions from intentional disposal. These munitions contain organic …
ordnance and munitions from intentional disposal. These munitions contain organic …