A probabilistic framework for particle-based reaction–diffusion dynamics using classical Fock space representations

MJ Del Razo, D Frömberg, AV Straube… - Letters in Mathematical …, 2022 - Springer
The modeling and simulation of stochastic reaction–diffusion processes is a topic of steady
interest that is approached with a wide range of methods. At the level of particle-resolved …

[HTML][HTML] Chemical diffusion master equation: Formulations of reaction–diffusion processes on the molecular level

MJ del Razo, S Winkelmann, R Klein… - Journal of Mathematical …, 2023 - pubs.aip.org
The chemical diffusion master equation (CDME) describes the probabilistic dynamics of
reaction–diffusion systems at the molecular level [del Razo et al., Lett. Math. Phys. 112, 49 …

Multiscale molecular kinetics by coupling Markov state models and reaction-diffusion dynamics

MJ Del Razo, M Dibak, C Schütte, F Noé - The Journal of Chemical …, 2021 - pubs.aip.org
A novel approach to simulate simple protein–ligand systems at large time and length scales
is to couple Markov state models (MSMs) of molecular kinetics with particle-based reaction …

Dynamics of systems with varying number of particles: from Liouville equations to general master equations for open systems

M del Razo, L Delle Site - SciPost Physics, 2025 - scipost.org
A varying number of particles is one of the most relevant characteristics of systems of interest
in nature and technology, ranging from the exchange of energy and matter with the …

MSM/RD: Coupling Markov state models of molecular kinetics with reaction-diffusion simulations

M Dibak, MJ Del Razo, D De Sancho… - The Journal of …, 2018 - pubs.aip.org
Molecular dynamics (MD) simulations can model the interactions between macromolecules
with high spatiotemporal resolution but at a high computational cost. By combining high …

Reversible interacting-particle reaction dynamics

C Fröhner, F Noé - The Journal of Physical Chemistry B, 2018 - ACS Publications
Interacting-particle reaction dynamics (iPRD) simulates the spatiotemporal evolution of
particles that experience interaction forces and can react with one another. The combination …

[HTML][HTML] Efficient reactive Brownian dynamics

A Donev, CY Yang, C Kim - The Journal of chemical physics, 2018 - pubs.aip.org
We develop a Split Reactive Brownian Dynamics (SRBD) algorithm for particle simulations
of reaction-diffusion systems based on the Doi or volume reactivity model, in which pairs of …

Coupling particle-based reaction-diffusion simulations with reservoirs mediated by reaction-diffusion pdes

M Kostré, C Schütte, F Noé, MJ Del Razo - Multiscale Modeling & Simulation, 2021 - SIAM
Open biochemical systems of interacting molecules are ubiquitous in life-related processes.
However, established computational methodologies, like molecular dynamics, are still …

Grand canonical diffusion-influenced reactions: A stochastic theory with applications to multiscale reaction-diffusion simulations

MJ Del Razo, H Qian, F Noé - The Journal of chemical physics, 2018 - pubs.aip.org
Smoluchowski-type models for diffusion-influenced reactions (A+ B→ C) can be formulated
within two frameworks: the probabilistic-based approach for a pair A, B of reacting particles …

Models for randomly distributed nanoscopic domains on spherical vesicles

VNP Anghel, D Bolmatov, J Katsaras - Physical Review E, 2018 - APS
The existence of lipid domains in the plasma membrane of biological systems has proven
controversial, primarily due to their nanoscopic size—a length scale difficult to interrogate …