Anhedonia in depression and schizophrenia: brain reward and aversion circuits

S Liang, Y Wu, L Hanxiaoran… - Neuropsychiatric …, 2022 - pmc.ncbi.nlm.nih.gov
Anhedonia, which is defined as markedly diminished interest or pleasure, is a prominent
symptom of psychiatric disorders, most notably major depressive disorder (MDD) and …

Negative symptoms and functioning in youth at risk of psychosis: a systematic review and meta-analysis

DJ Devoe, A Braun, T Seredynski… - Harvard review of …, 2020 - journals.lww.com
Aim Youth at CHR for psychosis often demonstrate significant negative symptoms and poor
functioning, though the magnitude and direction of the relationship between the two remains …

Clinical high risk for psychosis: the association between momentary stress, affective and psychotic symptoms

Y van der Steen, J Gimpel‐Drees… - Acta Psychiatrica …, 2017 - Wiley Online Library
Objective The aim of this study was to assess associations between momentary stress and
both affective and psychotic symptoms in everyday life of individuals at clinical high risk …

Anhedonia in adolescents at ultra-high risk (UHR) of psychosis: findings from a 1-year longitudinal study

L Pelizza, M Poletti, S Azzali, F Paterlini… - European Archives of …, 2020 - Springer
Previous findings suggested deficits in pleasure experience in schizophrenia, but little is
known in psychosis risk prodrome, especially in adolescence. Aim of this study was (1) to …

Pupillometer-based neurofeedback cognitive training to improve processing speed and social functioning in individuals at clinical high risk for psychosis.

J Choi, CM Corcoran, JM Fiszdon… - Psychiatric …, 2017 - psycnet.apa.org
Objective: Among individuals at clinical high risk (CHR) for psychosis, processing speed
(PS) has been related to social and role functioning regardless of conversion to …

Patient-reported outcome measures in clinical high risk for psychosis: a systematic review

J Addington, A Chao, A Braun, M Miller… - Schizophrenia Bulletin …, 2023 - academic.oup.com
A key issue in both research and clinical work with youth at clinical high risk (CHR) of
psychosis is that there are clearly heterogenous clinical outcomes in addition to the …

Diminished reward responsiveness is associated with lower reward network GluCEST: an ultra-high field glutamate imaging study

VJ Sydnor, B Larsen, C Kohler, AJD Crow… - Molecular …, 2021 - nature.com
Low reward responsiveness (RR) is associated with poor psychological well-being,
psychiatric disorder risk, and psychotropic treatment resistance. Functional MRI studies have …

Functional connectivity anomalies in adolescents with psychotic symptoms

F Amico, E O'Hanlon, D Kraft, V Oertel-Knöchel… - PLoS …, 2017 - journals.plos.org
Background Previous magnetic resonance imaging (MRI) research suggests that, prior to
the onset of psychosis, high risk youths already exhibit brain abnormalities similar to those …

6 Hz corneal kindling in mice triggers neurobehavioral comorbidities accompanied by relevant changes in c‐Fos immunoreactivity throughout the brain

G Albertini, L Walrave, T Demuyser, A Massie… - …, 2018 - Wiley Online Library
Objective Besides seizures, patients with epilepsy are affected by a variety of cognitive and
psychiatric comorbidities that further impair their quality of life. The present study provides an …

Acute effects of smoked marijuana in marijuana smokers at clinical high-risk for psychosis: A preliminary study

NP Vadhan, CM Corcoran, G Bedi, JG Keilp… - Psychiatry research, 2017 - Elsevier
Marijuana use is associated with psychosis, but its effects are understudied in individuals
with preexisting risk for psychotic disorders. This preliminary study examined the acute …