[HTML][HTML] Metal chelation therapy and Parkinson's disease: A critical review on the thermodynamics of complex formation between relevant metal ions and promising or …

M Tosato, V Di Marco - Biomolecules, 2019 - mdpi.com
The present review reports a list of approximately 800 compounds which have been used,
tested or proposed for Parkinson's disease (PD) therapy in the year range 2014–2019 …

Bisphosphonates: Future perspective for neurological disorders

S Zameer, AK Najmi, D Vohora, M Akhtar - Pharmacological Reports, 2018 - Elsevier
Neurodegenerative disorders and osteoporosis share some common underlying
pathological features including calcium overload, accumulation of toxic chemicals …

The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model

J Zhang, S An, W Hu, M Teng, X Wang, Y Qu… - International journal of …, 2016 - mdpi.com
Hericium erinaceus, an edible and medicinal mushroom, displays various pharmacological
activities in the prevention of dementia in conditions such as Parkinson's and Alzheimer's …

Moschus ameliorates glutamate-induced cellular damage by regulating autophagy and apoptosis pathway

D **e, C Song, T Qin, Z Zhai, J Cai, J Dai, T Sun… - Scientific Reports, 2023 - nature.com
Abstract Alzheimer's disease (AD), a neurodegenerative disorder, causes short-term
memory and cognition declines. It is estimated that one in three elderly people die from AD …

[HTML][HTML] Mitochondria Related Pathway Is Essential for Polysaccharides Purified from Sparassis crispa Mediated Neuro-Protection against Glutamate-Induced Toxicity …

S Hu, D Wang, J Zhang, M Du, Y Cheng, Y Liu… - International Journal of …, 2016 - mdpi.com
The present study aims to explore the neuro-protective effects of purified Sparassis crispa
polysaccharides against l-glutamic acid (l-Glu)-induced differentiated PC12 (DPC12) cell …

Synthesis of protocatechuic acid grafted chitosan copolymer: Structure characterization and in vitro neuroprotective potential

C Xu, S Guan, B Wang, S Wang, Y Wang, C Sun… - International Journal of …, 2018 - Elsevier
Excessive free radicals can cause oxidative damage to human tissues, which results in a
variety of diseases. Therefore, the development of antioxidant materials is one of the great …

Astaxanthin protects PC12 cells against homocysteine-and glutamate-induced neurotoxicity

CH Chang, KC Chen, KC Liaw, CC Peng, RY Peng - Molecules, 2020 - mdpi.com
Memory impairment has been shown to be associated with glutamate (Glu) excitotoxicity,
homocysteine (Hcy) accumulation, and oxidative stress. We hypothesize that Glu and Hcy …

Synergic temperature effect of star-like monodisperse iron oxide nanoparticles and their related responses in normal and cancer cells

M Kulpa-Greszta, M Wnuk… - The Journal of …, 2022 - ACS Publications
Magnetic nanoparticle (MNP) anisotropy has been tailored by the preparation of MNPs
having different shapes (star-like, cubic, and polyhedral) using a self-modified rapid hot …

A potential mechanism for the ameliorative effect of thymoquinone on pentylenetetrazole-induced kindling and cognitive impairments in mice

AO Abdel-Zaher, HSM Farghaly, MMY Farrag… - Biomedicine & …, 2017 - Elsevier
Cognitive dysfunction is commonly observed in epileptic patients. Pentylenetetrazole (PTZ)
kindling is a well established animal model which simulates clinical epilepsy. This study …

Seven new sesquineolignans isolated from the seeds of hawthorn and their neuroprotective activities

XX Huang, Q Ren, XY Song, L Zhou, GD Yao… - Fitoterapia, 2018 - Elsevier
Abstract Seven new sesquineolignans (1–7) were isolated from the 70% ethanolic extract of
the hawthorn seeds. Their structures were established by comprehensive spectroscopic …