[HTML][HTML] Saliva as a potential non-invasive liquid biopsy for early and easy diagnosis/prognosis of head and neck cancer

P Kumar, S Gupta, BC Das - Translational oncology, 2024 - Elsevier
Head and neck squamous cell carcinomas (HNSCCs) are the most devastating diseases in
India and southeast Asia. It is a preventable and curable disease if detected early. Tobacco …

Head and neck cancer

LQM Chow - New England Journal of Medicine, 2020 - Mass Medical Soc
Head and Neck Cancer Most head and neck cancers (73% in the United States) are now
related to human papillomavirus infection rather than tobacco and alcohol. Primary cancers …

Graph deep learning for the characterization of tumour microenvironments from spatial protein profiles in tissue specimens

Z Wu, AE Trevino, E Wu, K Swanson, HJ Kim… - Nature Biomedical …, 2022 - nature.com
Multiplexed immunofluorescence imaging allows the multidimensional molecular profiling of
cellular environments at subcellular resolution. However, identifying and characterizing …

Single-cell transcriptome profiling of the stepwise progression of head and neck cancer

JH Choi, BS Lee, JY Jang, YS Lee, HJ Kim… - Nature …, 2023 - nature.com
Head and neck squamous cell carcinoma (HNSCC) undergoes stepwise progression from
normal tissues to precancerous leukoplakia, primary HNSCC, and metastasized tumors. To …

Nivolumab plus ipilimumab versus EXTREME regimen as first-line treatment for recurrent/metastatic squamous cell carcinoma of the head and neck: the final results of …

RI Haddad, K Harrington, M Tahara… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE CheckMate 651 (ClinicalTrials. gov identifier: NCT02741570) evaluated first-line
nivolumab plus ipilimumab versus EXTREME (cetuximab plus cisplatin/carboplatin plus …

Safety and efficacy of nivolumab monotherapy in recurrent or metastatic cervical, vaginal, or vulvar carcinoma: results from the phase I/II CheckMate 358 trial

RW Naumann, A Hollebecque, T Meyer… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE Nivolumab was assessed in patients with virus-associated tumors in the phase
I/II CheckMate 358 trial (ClinicalTrials. gov identifier: NCT02488759). We report on patients …

Immune landscape of viral-and carcinogen-driven head and neck cancer

AR Cillo, CHL Kürten, T Tabib, Z Qi, S Onkar, T Wang… - Immunity, 2020 - cell.com
Head and neck squamous cell carcinoma (HNSCC) arises through exposure to
environmental carcinogens or malignant transformation by human papillomavirus (HPV) …

[HTML][HTML] Oncologic photodynamic therapy: basic principles, current clinical status and future directions

D Van Straten, V Mashayekhi, HS De Bruijn, S Oliveira… - Cancers, 2017 - mdpi.com
Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma

RL Ferris, W Westra - Annual Review of Pathology: Mechanisms …, 2023 - annualreviews.org
Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV-OPSCC)
has one of the most rapidly increasing incidences of any cancer in high-income countries …

Oral mucosal organoids as a potential platform for personalized cancer therapy

E Driehuis, S Kolders, S Spelier, K Lõhmussaar… - Cancer …, 2019 - aacrjournals.org
Previous studies have described that tumor organoids can capture the diversity of defined
human carcinoma types. Here, we describe conditions for long-term culture of human …