The evolution of plant NLR immune receptors and downstream signal components

Y Liu, YM Zhang, Y Tang, JQ Chen, ZQ Shao - Current opinion in plant …, 2023 - Elsevier
Along with the emergence of green plants on this planet one billion years ago, the
nucleotide binding site leucine-rich repeat (NLR) gene family originated and diverged into at …

[HTML][HTML] TIR-domain enzymatic activities at the heart of plant immunity

F Locci, J Wang, JE Parker - Current Opinion in Plant Biology, 2023 - Elsevier
Abstract Toll/interleukin-1/resistance (TIR) domain proteins contribute to innate immunity in
all cellular kingdoms. TIR modules are activated by self-association and in plants, mammals …

The N-terminal domains of NLR immune receptors exhibit structural and functional similarities across divergent plant lineages

KS Chia, J Kourelis, A Teulet, M Vickers, T Sakai… - The Plant …, 2024 - academic.oup.com
Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are a prominent class of
intracellular immune receptors in plants. However, our understanding of plant NLR structure …

Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products

AM Bayless, S Chen, SC Ogden, X Xu, JD Sidda… - Science …, 2023 - science.org
Toll/interleukin-1 receptor (TIR) domain proteins function in cell death and immunity. In
plants and bacteria, TIR domains are often enzymes that produce isomers of cyclic …

[HTML][HTML] Cytoplasmic calcium influx mediated by plant MLKLs confers TNL-triggered immunity

Q Shen, K Hasegawa, N Oelerich, A Prakken… - Cell Host & Microbe, 2024 - cell.com
The plant homolog of vertebrate necroptosis inducer mixed-lineage kinase domain-like
(MLKL) contributes to downstream steps in Toll-interleukin-1 receptor domain NLR (TNL) …

A canonical protein complex controls immune homeostasis and multipathogen resistance

Y Wu, W Xu, G Zhao, Z Lei, K Li, J Liu, S Huang… - Science, 2024 - science.org
The calcium (Ca2+) sensor ROD1 (RESISTANCE OF RICE TO DISEASES1) is a master
regulator of immunity in rice. By screening suppressors of rod1 mutants, we show that ROD1 …

Taking the lead: NLR immune receptor N‐terminal domains execute plant immune responses

KS Chia, P Carella - New Phytologist, 2023 - Wiley Online Library
Nucleotide‐binding domain and leucine‐rich repeat (NLR) proteins are important
intracellular immune receptors that activate robust plant immune responses upon detecting …

New biochemical principles for NLR immunity in plants

J Chai, W Song, JE Parker - Molecular Plant-Microbe …, 2023 - Am Phytopath Society
While working for the United States Department of Agriculture on the North Dakota
Agricultural College campus in Fargo, North Dakota, in the 1940s and 1950s, Harold H. Flor …

Plant NLR immunity activation and execution: a biochemical perspective

F Locci, JE Parker - Open Biology, 2024 - royalsocietypublishing.org
Plants deploy cell-surface and intracellular receptors to detect pathogen attack and trigger
innate immune responses. Inside host cells, families of nucleotide-binding/leucine-rich …

NLR immune receptors: structure and function in plant disease resistance

A Förderer, J Kourelis - Biochemical Society Transactions, 2023 - portlandpress.com
Nucleotide-binding and leucine-rich repeat receptors (NLRs) are a diverse family of
intracellular immune receptors that play crucial roles in recognizing and responding to …