Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

Growing evidence links COVID-19 with acute and long-term neurological dysfunction.
However, the pathophysiological mechanisms resulting in central nervous system …

Neuropsychiatric (NP) events occur in the majority of patients with SLE and predominantly
affect the CNS in addition to the peripheral and autonomic systems. Approximately 30% of …

The American College of Rheumatology's case definitions for 19 neuropsychiatric
syndromes in systemic lupus erythematosus (SLE) constitute a comprehensive classification …

Neurovascular defects are one of the most common alterations in Alzheimer's disease (AD)
pathogenesis, but whether these deficits develop before the onset of amyloid beta (Aβ) …

Inflammatory protein biomarkers induced by immune responses have been associated with
cognitive decline and the pathogenesis of Alzheimer's disease (AD). Here, we investigate …

Cognitive dysfunction (CD) is a common yet often clinically subtle manifestation that
considerably impacts the health-related quality of life in patients with systemic lupus …

The brain is an immune privileged organ, uniquely placed in the body. Two systems
involved in maintaining brain homeostasis and in protecting the brain are the blood-brain …

Blood brain barrier (BBB) is a group of astrocytes, neurons and endothelial cells, which
makes restricted passage of various biological or chemical entities to the brain tissue. It …