For centuries, gold had been considered a precious, purely decorative inert metal. It was not
until 1986 that Ito and Hayashi described the first application of gold (I) in homogeneous …

Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

Compounds having cyclic molecular frameworks are highly regarded for their abundance
and diverse utilities. In particular, medium-sized carbocycles and heterocycles exist in a …

Metal carbenes usually possess versatile reactivities that are controlled by the presence of
both the metals and the ligands. Diazo compounds are commonly used for the generation of …

Homogeneous gold-catalyzed cyclopropanation has emerged as a powerful method in
organic synthesis due to its rich chemistry and fascinating reactivity. This thriving strategy is …

N-Heterocyclic carbenes (NHCs) are cyclic carbenes bearing at least one R-amino
substituent. 1 The most common subclasses of NHCs are represented in Chart 1. Early work …

Gold salts and complexes have emerged in the past few years as the most powerful
catalysts for electrophilic activation of alkynes toward a variety of nucleophiles under …

Over the last two decades, electrophilic catalysis relying on platinum (II), gold (I), and gold
(III) salts has emerged as a remarkable synthetic methodology. Chemists have discovered a …

Cationic gold complexes in which gold is bound to a formally divalent carbon atom, typically
formulated as gold carbenes or α-metallocarbenium ions, have been widely invoked in a …

Allenes have proven themselves to be valuable building blocks toward complex molecular
targets, revealing novel applications in natural product synthesis, pharmaceutical chemistry …