Mechanistic insights into connexin-mediated neuroglia crosstalk in neurodegenerative diseases

S Denaro, S D'Aprile, N Vicario… - Frontiers in Cellular …, 2025 - frontiersin.org
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Multiple Sclerosis (MS), and Huntington's disease (HD), although distinct in their clinical …

[HTML][HTML] Neuroimmune regulation of the prefrontal cortex tetrapartite synapse

A Liss, MT Siddiqi, P Marsland, FP Varodayan - Neuropharmacology, 2025 - Elsevier
The prefrontal cortex (PFC) is an essential driver of cognitive, affective, and motivational
behavior. There is clear evidence that the neuroimmune system directly influences PFC …

Acute activation of hemichannels by ethanol leads to Ca2+-dependent gliotransmitter release in astrocytes

GI Gómez, C García-Rodríguez, JE Marillán… - Frontiers in Cell and …, 2024 - frontiersin.org
Multiple studies have demonstrated that acute ethanol consumption alters brain function and
cognition. Nevertheless, the mechanisms underlying this phenomenon remain poorly …

Hemichannels contribute to mitochondrial Ca2+ and morphology alterations evoked by ethanol in astrocytes

TF Alvear, A Farias-Pasten, SA Vergara… - Frontiers in Cell and …, 2024 - frontiersin.org
Alcohol, a toxic and psychoactive substance with addictive properties, severely impacts life
quality, leading to significant health, societal, and economic consequences. Its rapid …