Extended-spectrum-β-lactamase, AmpC, and carbapenemase issues

KS Thomson - Journal of clinical microbiology, 2010 - Am Soc Microbiol
Optimal use of microbiology laboratories is essential to combat the spread of multiply
antibiotic-resistant pathogens. This is vital for patient care, as advocated by Jarvis in …

[HTML][HTML] Acquired carbapenemases in Gram-negative bacterial pathogens: detection and surveillance issues

V Miriagou, G Cornaglia, M Edelstein, I Galani… - Clinical microbiology …, 2010 - Elsevier
Acquired carbapenemases are emerging resistance determinants in Gram-negative
pathogens, including Enterobacteriaceae, Pseudomonas aeruginosa and other Gram …

[HTML][HTML] Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories

J Hrabák, E Chudáčková, CC Papagiannitsis - Clinical Microbiology and …, 2014 - Elsevier
Carbapenemase-producing bacteria have now spread all over the world. Infections caused
by those bacteria are difficult to treat. Therefore, there is an urgent need for accurate and fast …

How to detect carbapenemase producers? A literature review of phenotypic and molecular methods

D Hammoudi, CA Moubareck, DK Sarkis - Journal of microbiological …, 2014 - Elsevier
This review describes the current state-of-art of carbapenemase detection methods.
Identification of carbapenemases is first based on conventional phenotypic tests including …

Antimicrobial and Diagnostic Stewardship of the Novel β-Lactam/β-Lactamase Inhibitors for Infections Due to Carbapenem-Resistant Enterobacterales Species and …

S Ferous, C Anastassopoulou, V Pitiriga, G Vrioni… - Antibiotics, 2024 - mdpi.com
Carbapenem-resistant Gram-negative bacterial infections are a major public health threat
due to the limited therapeutic options available. The introduction of the new β-lactam/β …

Long period fiber grating working in reflection mode as valuable biosensing platform for the detection of drug resistant bacteria

G Quero, S Zuppolini, M Consales, L Diodato… - Sensors and Actuators B …, 2016 - Elsevier
We report here on a reflection-type long period fiber grating (RT-LPG) biosensor for the fast
detection of class C (AmpC) β-lactamases (BLs), actually considered as one of the most …

Label-free fiber optic optrode for the detection of class C β-lactamases expressed by drug resistant bacteria

S Zuppolini, G Quero, M Consales, L Diodato… - Biomedical Optics …, 2017 - opg.optica.org
This paper reports the experimental assessment of an automated optical assay based on
label free optical fiber optrodes for the fast detection of class C β-lactamases (AmpC BLs) …

Investigation of metallo beta lactamases and oxacilinases in carbapenem resistant Acinetobacter baumannii strains isolated from inpatients

MD Aksoy, Ş Çavuşlu, HM Tuğrul - Balkan medical journal, 2015 - dergipark.org.tr
Background: Resistance to beta-lactam antibiotics is widespread among Acinetobacter
strains. Plasmid-mediated metallo beta lactamases (MBL) are responsible for carbapenem …

Prevalence and Antibiotic Susceptibility Patterns of Extended-Spectrum ß-Lactamase and Metallo-ß-Lactamase–Producing Uropathogenic Escherichia coli Isolates

H Ghadiri, H Vaez, K Razavi-Azarkhiavi… - Laboratory …, 2014 - academic.oup.com
Healthcare professionals worldwide have expressed concern over infections by extended-
spectrum ß-lactamase (ESBL) and metallo-ß-lactamase (MBL)–producing bacteria. We …

[HTML][HTML] False positive phenotypic detection of metallo-beta-lactamases in Acinetobacter baumannii

B Bedenić, R Ladavac, M Vranić-Ladavac… - Acta clinica …, 2019 - ncbi.nlm.nih.gov
Phenotypic detection of metallo-β-lactamases (MBLs) in Acinetobacter (A.) baumannii is a
serious challenge to clinical microbiologists. MBLs are inhibited by metal chelators such as …