[HTML][HTML] Invasive candidiasis

PG Pappas, MS Lionakis, MC Arendrup… - Nature Reviews …, 2018 - nature.com
Invasive candidiasis is an important health-care-associated fungal infection that can be
caused by several Candida spp.; the most common species is Candida albicans, but the …

Invasive candidiasis

BJ Kullberg, MC Arendrup - New England Journal of Medicine, 2015 - Mass Medical Soc
Despite advances in antifungal therapy, the mortality associated with invasive candidiasis
remains as high as 40%. This review summarizes recent trends and current strategies …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Clinical practice guideline for the management of candidiasis: 2016 update by the Infectious Diseases Society of America

PG Pappas, CA Kauffman, DR Andes… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Candida albicans Biofilms and Human Disease

CJ Nobile, AD Johnson - Annual review of microbiology, 2015 - annualreviews.org
In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

The antifungal pipeline: a reality check

JR Perfect - Nature reviews Drug discovery, 2017 - nature.com
Invasive fungal infections continue to appear in record numbers as the
immunocompromised population of the world increases, owing partially to the increased …

Development and regulation of single- and multi-species Candida albicans biofilms

MB Lohse, M Gulati, AD Johnson… - Nature Reviews …, 2018 - nature.com
Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients

F Tissot, S Agrawal, L Pagano, G Petrikkos… - …, 2016 - pmc.ncbi.nlm.nih.gov
The European Conference on Infections in Leukemia (ECIL) provides recommendations for
diagnostic strategies and prophylactic, pre-emptive or targeted therapy strategies for various …

ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non‐neutropenic adult patients

OA Cornely, M Bassetti, T Calandra… - Clinical Microbiology …, 2012 - Wiley Online Library
Clin Microbiol Infect 2012; 18 (Suppl. 7): 19–37 Abstract This part of the EFISG guidelines
focuses on non‐neutropenic adult patients. Only a few of the numerous recommendations …

[HTML][HTML] Candida albicans biofilms: development, regulation, and molecular mechanisms

M Gulati, CJ Nobile - Microbes and infection, 2016 - Elsevier
A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed
communities of cells adhered to a surface. These biofilms are intrinsically resistant to …