Incorporation of a rigid 1, 3-diketone-containing fragment led to significantly improved AXL inhibitory activity: design, synthesis, and SAR of the anilinopyrimidine AXL …

W Hu, X Peng, Y Ji, W Duan, J Ai, Z Zhan - Molecular Diversity, 2024 - Springer
Overexpressed AXL kinase is involved in various human malignancies, which incurs tumor
progression, poor prognosis, and drug resistance. Suppression of the aberrant AXL axis with …