Stimuli-responsive polymersomes for cancer therapy

T Thambi, DS Lee - Stimuli responsive polymeric nanocarriers for drug …, 2019 - Elsevier
Cancer is the most common life-threatening illness and remains the leading cause of death
in the United States. Nanomedicine represents an innovative field and has an incredible …

Hypoxia-responsive nanocarriers for cancer imaging and therapy: recent approaches and future perspectives

T Thambi, JH Park, DS Lee - Chemical Communications, 2016 - pubs.rsc.org
Hypoxia, a condition in which the tissue is deprived of adequate oxygen supply, is a salient
feature of various intractable diseases, including rheumatoid arthritis, ischemic stroke, and …

In situ diselenide-crosslinked polymeric micelles for ROS-mediated anticancer drug delivery

VG Deepagan, S Kwon, DG You, W Um, H Ko, H Lee… - Biomaterials, 2016 - Elsevier
Stimuli-responsive micelles have emerged as the drug carrier for cancer therapy since they
can exclusively release the drug via their structural changes in response to the specific …

DePEGylation strategies to increase cancer nanomedicine efficacy

L Kong, F Campbell, A Kros - Nanoscale horizons, 2019 - pubs.rsc.org
To maximize drug targeting to solid tumors, cancer nanomedicines with prolonged
circulation times are required. To this end, poly (ethylene glycol)(PEG) has been widely …

Production of minor ginsenoside CK from major ginsenosides by biotransformation and its advances in targeted delivery to tumor tissues using nanoformulations

M Murugesan, R Mathiyalagan, V Boopathi, BM Kong… - Nanomaterials, 2022 - mdpi.com
For over 2000 years, ginseng (roots of Panax ginseng CA Meyer) has been used as a
traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng …

Bioreducible shell-cross-linked hyaluronic acid nanoparticles for tumor-targeted drug delivery

HS Han, T Thambi, KY Choi, S Son, H Ko… - …, 2015 - ACS Publications
The major issues of self-assembled nanoparticles as drug carriers for cancer therapy
include biostability and tumor-targetability because the premature drug release from and …

One-step preparation of pH-responsive polymeric nanogels as intelligent drug delivery systems for tumor therapy

Y Li, QN Bui, LTM Duy, HY Yang, DS Lee - Biomacromolecules, 2018 - ACS Publications
In this work, pH-responsive polypeptide-based nanogels are reported as potential drug
delivery systems. By the formation of pH-sensitive benzoic imine bonds, pH-responsive …

Stimuli-responsive polymers for anti-cancer drug delivery

W Cheng, L Gu, W Ren, Y Liu - Materials Science and Engineering: C, 2014 - Elsevier
Stimuli-responsive polymers are an important component for preparation of stimuli-
responsive drug delivery systems with less side effects and improved efficacy for cancer …

Integrated and hyaluronic acid-coated mesoporous silica nanoparticles conjugated with cisplatin and chlorin e6 for combined chemo and photodynamic cancer …

Y Li, VHG Phan, Z Pan, X Xuan, HY Yang… - European Polymer …, 2024 - Elsevier
To enhance antitumor efficacy and overcome multidrug resistance, the targeted delivery of
photosensitizers and chemotherapeutic agents holds great promise for improving anticancer …

Disulfide-linked amphiphilic polymer-docetaxel conjugates assembled redox-sensitive micelles for efficient antitumor drug delivery

P Zhang, H Zhang, W He, D Zhao, A Song… - …, 2016 - ACS Publications
Here, we prepared novel redox-sensitive drug delivery system based on copolymer-drug
conjugates methoxy poly (ethylene glycol)-poly (γ-benzyl l-glutamate)-disulfide-docetaxel …