Mitoxantrone-surfactant interactions: a physicochemical overview

M Enache, AM Toader, MI Enache - Molecules, 2016 - mdpi.com
Mitoxantrone is a synthetic anticancer drug used clinically in the treatment of different types
of cancer. It was developed as a doxorubicin analogue in a program to find drugs with …

Anthracycline antibiotics detection using turn-off luminescent nanosensors

DV Tsyupka, YA Podkolodnaya, EA Khudina… - TrAC Trends in …, 2024 - Elsevier
Anthracycline antibiotics (doxorubicin, daunorubicin, mitoxantrone, idarubicin, epirubicin,
ect.) are widely used in chemotherapy of various diseases, effectively destroying cancer …

Role of hydrotropes in sparingly soluble drug solubilization: insight from a molecular dynamics simulation and experimental perspectives

R Paul, KG Chattaraj, S Paul - Langmuir, 2021 - ACS Publications
Drug molecules' therapeutic efficacy depends on their bioavailability and solubility. But more
than 70% of the formulated drug molecules show limited effectiveness due to low water …

Studies on self-aggregation of anthracycline drugs by restrained molecular dynamics approach using nuclear magnetic resonance spectroscopy supported by …

P Agrawal, SK Barthwal, R Barthwal - European journal of medicinal …, 2009 - Elsevier
Self-association, a process that competes with binding to DNA and formation of hetero-
complexes, is studied in anticancer drugs 4′-epiadriamycin, adriamycin and daunomycin …

Luminescence behavior of colloid quantum dots in the presence anthracycline antibiotic mitoxantrone: Surface interaction and luminescence quenching, size and …

DV Tsyupka, EA Mordovina, TS Ponomaryova… - Colloids and Surfaces A …, 2023 - Elsevier
The luminescence of colloidal quantum dots (QDs) is often affected by the passivating layer,
the stabilizing ligand, and the interactions in solution. The anthracycline antibiotic …

An eco‐friendly matrix‐augmented fluorescence spectroscopic approach for the analysis of mitoxantrone, an oncogenic therapy; application to the dosage form and …

AA Hamad, YF Hassan, WE Eltoukhi… - …, 2023 - Wiley Online Library
Mitoxantrone (MXN) is a synthetic anthracenedione oncogenic therapy. It is often prescribed
as an anticancer agent to manage a variety of cancers. A green, fast, and easy fluorimetric …

Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by novantrone (mitoxantrone)

S Zheng, Y Chen, CP Donahue, MS Wolfe, G Varani - Chemistry & biology, 2009 - cell.com
Some familial neurodegenerative diseases are associated with mutations that destabilize a
putative stem-loop structure within an intronic region of the tau pre-messenger RNA (mRNA) …

Parallel stacking of caffeine with riboflavin in aqueous solutions: the potential mechanism for hydrotropic solubilization of riboflavin

Y Cui - International journal of pharmaceutics, 2010 - Elsevier
Hydrotropy is a phenomenon where the presence of a large quantity of one solute enhances
the solubility of another solute. The mechanism of this phenomenon remains elusive and a …

[HTML][HTML] A 4: 1 stoichiometric binding and stabilization of mitoxantrone-parallel stranded G-quadruplex complex established by spectroscopy techniques

TP Pradeep, R Barthwal - Journal of Photochemistry and Photobiology B …, 2016 - Elsevier
Small molecule ligands which specifically bind and stabilize G-quadruplex structures in
telomeric ends inhibit the activity of telomerase enzyme, an important marker for cancer …

Hetero-association of aromatic molecules in aqueous solution

MP Evstigneev - International Reviews in Physical Chemistry, 2014 - Taylor & Francis
Knowledge of the physical chemistry of small molecules complexation (the hetero-
association) in aqueous solution is increasingly important in view of the rapidly emerging …