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RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Nanomaterials for bone metastasis
X Hao, B Jiang, J Wu, D **ang, Z **ong, C Li… - Journal of Controlled …, 2024 - Elsevier
Bone metastasis, a prevalent occurrence in primary malignant tumors, is often associated
with a grim prognosis. The bone microenvironment comprises various coexisting cell types …
with a grim prognosis. The bone microenvironment comprises various coexisting cell types …
Non-coding RNAs and potential therapeutic targeting in cancer
Recent advances have begun to clarify the physiological and pathological roles of non-
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
coding RNAs (ncRNAs) in various diseases, including cancer. Among these, microRNAs …
Epidrugs: targeting epigenetic marks in cancer treatment
Growing evidence suggests that aberrant epigenetic regulation of gene function is strongly
related to the genesis of cancer. Unlike genetic mutations, the ability to reprogram the …
related to the genesis of cancer. Unlike genetic mutations, the ability to reprogram the …
Autophagy as a molecular target for cancer treatment
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …
[HTML][HTML] MicroRNA therapeutics in cancer: current advances and challenges
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …
[HTML][HTML] A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
microRNA therapeutics in cancer—an emerging concept
MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
RNAs that negatively regulate protein coding gene and other non-coding transcripts …
The progress and promise of RNA medicine─ an arsenal of targeted treatments
In the past decade, there has been a shift in research, clinical development, and commercial
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
activity to exploit the many physiological roles of RNA for use in medicine. With the rapid …
Treating cancer with microRNA replacement therapy: A literature review
microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …