Thrombosis as an intravascular effector of innate immunity

B Engelmann, S Massberg - Nature Reviews Immunology, 2013 - nature.com
Thrombosis is the most frequent cause of mortality worldwide and is closely linked to
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …

Regulation of VWF (von Willebrand factor) in inflammatory thrombosis

XD Manz, HJ Bogaard, J Aman - Arteriosclerosis, thrombosis, and …, 2022 - ahajournals.org
Increasing evidence indicates that inflammation promotes thrombosis via a VWF (von
Willebrand factor)-mediated mechanism. VWF plays an essential role in maintaining the …

[HTML][HTML] Prominent changes in blood coagulation of patients with SARS-CoV-2 infection

H Han, L Yang, R Liu, F Liu, K Wu, J Li… - Clinical Chemistry and …, 2020 - degruyter.com
Background As the number of patients increases, there is a growing understanding of the
form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has …

COVID-19-associated coagulopathy: an exacerbated immunothrombosis response

A Jayarangaiah, PT Kariyanna… - Clinical and Applied …, 2020 - journals.sagepub.com
Since the onset of the global pandemic in early 2020, coronavirus disease 2019 (COVID-19)
has posed a multitude of challenges to health care systems worldwide. In order to combat …

Pathogenesis of Staphylococcus aureus Bloodstream Infections

L Thomer, O Schneewind… - Annual Review of …, 2016 - annualreviews.org
Staphylococcus aureus, a Gram-positive bacterium colonizing nares, skin, and the
gastrointestinal tract, frequently invades the skin, soft tissues, and bloodstreams of humans …

[HTML][HTML] The coagulation system in host defense

S Antoniak - Research and Practice in Thrombosis and …, 2018 - Elsevier
The blood coagulation system and immune system of higher organisms are thought to have
a common ancestral origin. During infections, the blood coagulation system is activated and …

Blood coagulation in immunothrombosis—at the frontline of intravascular immunity

F Gaertner, S Massberg - Seminars in immunology, 2016 - Elsevier
While hemostasis is the physiological process that prevents blood loss after vessel injury,
thrombosis is often portrayed as a pathologic event involving blood coagulation and platelet …

Insect immunity to entomopathogenic fungi

HL Lu, RJS Leger - Advances in genetics, 2016 - Elsevier
The study of infection and immunity in insects has achieved considerable prominence with
the appreciation that their host defense mechanisms share many fundamental …

Impact of neutrophil extracellular traps on thrombosis formation: new findings and future perspective

Y Zhou, Z Xu, Z Liu - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
Thrombotic diseases seriously endanger human health, neutrophils and neutrophil
extracellular traps (NETs) play an important role in abnormal thrombus formation. NETs are …

Platelets in pulmonary immune responses and inflammatory lung diseases

EA Middleton, AS Weyrich… - Physiological …, 2016 - journals.physiology.org
Platelets are essential for physiological hemostasis and are central in pathological
thrombosis. These are their traditional and best known activities in health and disease. In …