Bacterial small RNA regulators: versatile roles and rapidly evolving variations
S Gottesman, G Storz - Cold Spring Harbor perspectives …, 2011 - cshperspectives.cshlp.org
Small RNA regulators (sRNAs) have been identified in a wide range of bacteria and found to
play critical regulatory roles in many processes. The major families of sRNAs include true …
play critical regulatory roles in many processes. The major families of sRNAs include true …
Regulation of bacterial virulence by Csr (Rsm) systems
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …
and in specialized host niches. This ability requires their metabolism, physiology, and …
Gac/Rsm signal transduction pathway of γ‐proteobacteria: from RNA recognition to regulation of social behaviour
In many γ‐proteobacteria, the conserved GacS/GacA (BarA/UvrY) two‐component system
positively controls the expression of one to five genes specifying small RNAs (sRNAs) that …
positively controls the expression of one to five genes specifying small RNAs (sRNAs) that …
The GacS/GacA signal transduction system of Pseudomonas aeruginosa acts exclusively through its control over the transcription of the RsmY and RsmZ regulatory …
A Brencic, KA McFarland, HR McManus… - Molecular …, 2009 - Wiley Online Library
We report here the results of an analysis of the regulatory range of the GacS/GacA two‐
component system in Pseudomonas aeruginosa. Using microarrays, we identified a large …
component system in Pseudomonas aeruginosa. Using microarrays, we identified a large …
CsrB sRNA family: sequestration of RNA-binding regulatory proteins
Noncoding regulatory RNA molecules, also known as small RNAs, participate in several
bacterial regulatory networks. The central component of the carbon storage regulator (Csr) …
bacterial regulatory networks. The central component of the carbon storage regulator (Csr) …
Post‐transcriptional regulation on a global scale: form and function of Csr/Rsm systems
Originally described as a repressor of gene expression in the stationary phase of growth,
CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation …
CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation …
RNA-binding proteins involved in post-transcriptional regulation in bacteria
E Van Assche, S Van Puyvelde… - Frontiers in …, 2015 - frontiersin.org
Post-transcriptional regulation is a very important mechanism to control gene expression in
changing environments. In the past decade, a lot of interest has been directed toward the …
changing environments. In the past decade, a lot of interest has been directed toward the …
The Life Cycle of L. pneumophila: Cellular Differentiation Is Linked to Virulence and Metabolism
G Oliva, T Sahr, C Buchrieser - Frontiers in cellular and infection …, 2018 - frontiersin.org
Legionella pneumophila is a gram-negative bacterium that inhabits freshwater ecosystems,
where it is present in biofilm or as planktonic form. L. pneumophila is mainly found …
where it is present in biofilm or as planktonic form. L. pneumophila is mainly found …
Post-transcriptional global regulation by CsrA in bacteria
J Timmermans, L Van Melderen - Cellular and molecular life sciences, 2010 - Springer
Global regulation allows bacteria to rapidly modulate the expression of a large variety of
unrelated genes in response to environmental changes. Global regulators act at different …
unrelated genes in response to environmental changes. Global regulators act at different …
Small noncoding RNAs controlling pathogenesis
Infectious diseases are a leading cause of mortality worldwide. A major challenge in
achieving their eradication is a better understanding of bacterial pathogenesis processes …
achieving their eradication is a better understanding of bacterial pathogenesis processes …