This review focuses on recent trends in multiple sequence alignment tools. It describes the
latest algorithmic improvements including the extension of consistency-based methods to …

An ever-increasing number of biological modeling methods depend on the assembly of an
accurate multiple sequence alignment (MSA). These include phylogenetic trees, profiles …

Inference of multiple sequence alignments (MSAs) is a critical part of phylogenetic and
comparative genomics studies. However, from the same set of sequences different MSAs …

Background Alignment of large and diverse sequence sets is a common task in biological
investigations, yet there remains considerable room for improvement in alignment quality …

Jalview Version 2 is a system for interactive WYSIWYG editing, analysis and annotation of
multiple sequence alignments. Core features include keyboard and mouse-based editing …

Alignment quality may have as much impact on phylogenetic reconstruction as the
phylogenetic methods used. Not only the alignment algorithm, but also the method used to …

Multiple comparison or alignmentof protein sequences has become a fundamental tool in
many different domains in modern molecular biology, from evolutionary studies to prediction …

Multiple sequence alignments (MSAs) are a prerequisite for a wide variety of evolutionary
analyses. Published assessments and benchmark data sets for protein and, to a lesser …

Background Multiple sequence alignment (MSA) is an extremely useful tool for molecular
and evolutionary biology and there are several programs and algorithms available for this …

I have addressed the biological rather than bioinformatics aspects of molecular sequence
alignment by covering a series of topics that have been under-valued, particularly within the …