Point‐of‐care testing in haemostasis
DJ Perry, DA Fitzmaurice, S Kitchen… - British Journal of …, 2010 - Wiley Online Library
Point‐of‐care testing (POCT) in haematology has seen a significant increase in both the
spectrum of tests available and the number of tests performed annually. POCT is frequently …
spectrum of tests available and the number of tests performed annually. POCT is frequently …
The GPIIb/IIIa (integrin αIIbβ3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend
BS Coller, SJ Shattil - Blood, The Journal of the American …, 2008 - ashpublications.org
Starting 90 years ago with a clinical description by Glanzmann of a bleeding disorder
associated with a defect in platelet function, technologic advances helped investigators …
associated with a defect in platelet function, technologic advances helped investigators …
Guidelines for the laboratory investigation of heritable disorders of platelet function
The guideline writing group was selected to be representative of UK‐based medical experts.
MEDLINE was systematically searched for publications in English up to the Summer of 2010 …
MEDLINE was systematically searched for publications in English up to the Summer of 2010 …
Interindividual variability in the response to oral antiplatelet drugs: a position paper of the Working Group on antiplatelet drugs resistance appointed by the Section of …
W Kuliczkowski, A Witkowski, L Polonski… - European heart …, 2009 - academic.oup.com
Oral antiplatelet drugs are a cornerstone of modern pharmacotherapy in cardiovascular
atherothrombotic diseases. The efficacy of acetylsalicylic acid (ASA, aspirin) and clopidogrel …
atherothrombotic diseases. The efficacy of acetylsalicylic acid (ASA, aspirin) and clopidogrel …
Methods for the measurement of platelet function
AD Michelson - The American journal of cardiology, 2009 - Elsevier
This article discusses the advantages and disadvantages of methods for the measurement
of platelet function. The focus is on tests that can be used to monitor antiplatelet activity in …
of platelet function. The focus is on tests that can be used to monitor antiplatelet activity in …
Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial
AD Michelson, AL Frelinger III, E Braunwald… - European heart …, 2009 - academic.oup.com
Aims To examine the extent of platelet inhibition by prasugrel vs. clopidogrel in a TRITON-
TIMI 38 substudy. Methods and results TRITON-TIMI 38 randomized acute coronary …
TIMI 38 substudy. Methods and results TRITON-TIMI 38 randomized acute coronary …
Comparison of current platelet functional tests for the assessment of aspirin and clopidogrel response
S Le Quellec, JC Bordet, C Negrier… - Thrombosis and …, 2016 - thieme-connect.com
The two most widely used antiplatelet drugs in the world are aspirin and clopidogrel.
However, some patients on aspirin and/or clopidogrel therapy do not respond appropriately …
However, some patients on aspirin and/or clopidogrel therapy do not respond appropriately …
Chronic kidney disease is associated with increased platelet activation and poor response to antiplatelet therapy
T Gremmel, M Müller, S Steiner… - Nephrology Dialysis …, 2013 - academic.oup.com
Background Chronic kidney disease (CKD) is a common co-morbidity of patients with
atherosclerotic vascular disease, and may influence the response to antiplatelet therapy …
atherosclerotic vascular disease, and may influence the response to antiplatelet therapy …
[HTML][HTML] Different methodologies for evaluating the effect of clopidogrel on platelet function in high‐risk coronary artery disease patients
Background: Two point‐of‐care (POC) systems have been recently proposed as rapid tools
with which to evaluate residual platelet reactivity (RPR) in coronary artery disease (CAD) …
with which to evaluate residual platelet reactivity (RPR) in coronary artery disease (CAD) …
Antiplatelet actions of statins and fibrates are mediated by PPARs
FY Ali, PCJ Armstrong, ARA Dhanji… - … , and vascular biology, 2009 - Am Heart Assoc
Objectives—Statins and fibrates are hypolipidemic drugs which decrease cardiac events in
individuals without raised levels of cholesterol. These drugs inhibit platelet function, but the …
individuals without raised levels of cholesterol. These drugs inhibit platelet function, but the …