[HTML][HTML] Targeting Hippo pathway: a novel strategy for Helicobacter pylori-induced gastric cancer treatment

Y Liu, B Zhang, Y Zhou, Y **ng, Y Wang, Y Jia… - Biomedicine & …, 2023 - Elsevier
The Hippo pathway plays an important role in cell proliferation, apoptosis, and
differentiation; it is a crucial regulatory pathway in organ development and tumor growth …

Natural products targeting signaling pathways associated with regulated cell death in gastric cancer: Recent advances and perspectives

Q Hu, Z Li, Y Li, X Deng, Y Chen, X Ma… - Phytotherapy …, 2023 - Wiley Online Library
Gastric cancer (GC) is one of the most serious gastrointestinal malignancies with high
morbidity and mortality. The complexity of GC process lies in the multi‐phenotypic linkage …

UBR2 enriched in p53 deficient mouse bone marrow mesenchymal stem cell-exosome promoted gastric cancer progression via Wnt/β-catenin pathway

J Mao, Z Liang, B Zhang, H Yang, X Li, H Fu… - Stem Cells, 2017 - academic.oup.com
The deficiency or mutation of p53 has been linked to several types of cancers. The
mesenchymal stem cell (MSC) is an important component in the tumor microenvironment …

[HTML][HTML] The importance of CXCL1 in the physiological state and in noncancer diseases of the oral cavity and abdominal organs

J Korbecki, I Szatkowska, P Kupnicka… - International Journal of …, 2022 - mdpi.com
CXCL1 is a CXC chemokine, CXCR2 ligand and chemotactic factor for neutrophils. In this
paper, we present a review of the role of the chemokine CXCL1 in physiology and in …

An overview of selected bacterial infections in cancer, their virulence factors, and some aspects of infection management

A Ray, TF Moore, R Pandit, AD Burke, DM Borsch - Biology, 2023 - mdpi.com
Simple Summary Bacterial involvement in cancer can be grouped into three categories:(i)
direct association of bacteria in the processes of cancer development,(ii) secondary infection …

Gastric Damage and Cancer-Associated Biomarkers in Helicobacter pylori-Infected Children

S George, Y Lucero, JP Torres… - Frontiers in …, 2020 - frontiersin.org
Helicobacter pylori (H. pylori) is well-known to be involved in gastric carcinogenesis,
associated with deregulation of cell proliferation and epigenetic changes in cancer-related …

Negative feedback loop in the activation of non-homologous end joining DNA repair pathway in Helicobacter pylori infected patients with gastritis

M Amirnorouzi, A Karimi, NE Daryani, A Rajaei… - Scientific Reports, 2024 - nature.com
This study aimed to investigate the activation of error-prone DNA repair pathway in response
to Helicobacter pylori infection. Relative changes in the expression levels of genes involved …

The bacterial microbiota of gastrointestinal cancers: role in cancer pathogenesis and therapeutic perspectives

L Elsalem, AA Jum'ah, MA Alfaqih… - Clinical and …, 2020 - Taylor & Francis
The microbiota has an essential role in the pathogenesis of many gastrointestinal diseases
including cancer. This effect is mediated through different mechanisms such as damaging …

Lactobacillus plantarum induces apoptosis in gastric cancer cells via modulation of signaling pathways in Helicobacter pylori

H Maleki-Kakelar, J Dehghani, A Barzegari… - BioImpacts …, 2019 - pmc.ncbi.nlm.nih.gov
Introduction: Gastric cancer is considered the second prevalent cause of death around the
world. This type of cancer is generally induced by Helicobacter pylori which could colonize …

DNA damage repair and current therapeutic approaches in gastric cancer: A comprehensive review

M Wang, C **e - Frontiers in Genetics, 2022 - frontiersin.org
DNA in cells is frequently damaged by endogenous and exogenous agents. However,
comprehensive mechanisms to combat and repair DNA damage have evolved to ensure …