MicroRNA-based diagnosis and therapy

PTB Ho, IM Clark, LTT Le - International journal of molecular sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …

Overview of microRNA biogenesis, mechanisms of actions, and circulation

J O'Brien, H Hayder, Y Zayed, C Peng - Frontiers in endocrinology, 2018 - frontiersin.org
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …

Beneficial and detrimental aspects of miRNAs as chief players in breast cancer: a comprehensive review

A Ismail, HA El-Mahdy, AI Abulsoud… - International Journal of …, 2023 - Elsevier
Breast cancer (BC) is the most common cancer in women and poses a serious threat to their
health. Despite familiarity with factors affecting its etiology, initiation, progression, treatment …

[HTML][HTML] Sunitinib resistance in renal cell carcinoma: From molecular mechanisms to predictive biomarkers

J **, Y **e, JS Zhang, JQ Wang, SJ Dai, W He… - Drug Resistance …, 2023 - Elsevier
Currently, renal cell carcinoma (RCC) is the most prevalent type of kidney cancer. Targeted
therapy has replaced radiation therapy and chemotherapy as the main treatment option for …

Stress-induced perinatal and transgenerational epigenetic programming of brain development and mental health

O Babenko, I Kovalchuk, GAS Metz - Neuroscience & Biobehavioral …, 2015 - Elsevier
Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets

M Ghafourian, R Mahdavi, Z Akbari Jonoush… - Cell Communication and …, 2022 - Springer
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

MiRNA-210: a current overview

A Bavelloni, G Ramazzotti, A Poli, M Piazzi… - Anticancer …, 2017 - ar.iiarjournals.org
microRNAs (miRNAs) are a group of highly conserved small non-coding RNAs that were
found to enhance mRNA degradation or inhibit post-transcriptional translation. Accumulating …

The role of epigenetics in placental development and the etiology of preeclampsia

C Apicella, CSM Ruano, C Méhats, F Miralles… - International journal of …, 2019 - mdpi.com
In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …

MicroRNAs: crucial regulators of placental development

H Hayder, J O'Brien, U Nadeem, C Peng - Reproduction, 2018 - rep.bioscientifica.com
MicroRNAs (miRNAs) are small non-coding single-stranded RNAs that are integral to a wide
range of cellular processes mainly through the regulation of translation and mRNA stability …

Non-coding RNA: role in gestational diabetes pathophysiology and complications

T Filardi, G Catanzaro, S Mardente, A Zicari… - International Journal of …, 2020 - mdpi.com
Gestational Diabetes Mellitus (GDM) is defined as glucose intolerance that develops in the
second or third trimester of pregnancy. GDM can lead to short-term and long-term …