Plague

MB Prentice, L Rahalison - The Lancet, 2007 - thelancet.com
Bubonic plague is an often fulminant systemic zoonosis, caused by Yersinia pestis.
Conventional microbiology, bacterial population genetics, and genome sequence data, all …

Phage-based platforms for the clinical detection of human bacterial pathogens

D Schofield, NJ Sharp, C Westwater - Bacteriophage, 2012 - Taylor & Francis
Bacteriophages (phages) have been utilized for decades as a means for uniquely identifying
their target bacteria. Due to their inherent natural specificity, ease of use, and straightforward …

Prevention and treatment of colitis with Lactococcus lactis secreting the immunomodulatory Yersinia LcrV protein

B Foligne, R Dessein, M Marceau, S Poiret… - Gastroenterology, 2007 - Elsevier
Background & Aims: The low calcium response V (LcrV) protein synthesized by gram-
negative, pathogenic yersiniae participates in bacterial evasion of the host's innate immune …

Magnetic biosensor for the detection of Yersinia pestis

MHF Meyer, M Stehr, S Bhuju, HJ Krause… - Journal of …, 2007 - Elsevier
A novel type of magnetic-beads based magnetic biosensor is described for the detection of
Yersinia pestis. Experiments were performed with the antigen fraction F1 of these bacteria …

Critical Comparison between Large and Mini Vertical Flow Immunoassay Platforms for Yersinia Pestis Detection

JP Devadhasan, J Gu, P Chen, S Smith… - Analytical …, 2021 - ACS Publications
Yersinia pestis is a Gram-negative bacterium that is the causative agent of plague and is
widely recognized as a potential biological weapon. Due to the high fatality rate of plague …

Evaluation of Up-Converting Phosphor Technology-Based Lateral Flow Strips for Rapid Detection of Bacillus anthracis Spore, Brucella spp., and Yersinia pestis

P Zhang, X Liu, C Wang, Y Zhao, F Hua, C Li, R Yang… - PloS one, 2014 - journals.plos.org
Bacillus anthracis, Brucella spp., and Yersinia pestis are zoonotic pathogens and biowarfare-
or bioterrorism-associated agents that must be detected rapidly on-site from various samples …

Development of a dual antigen lateral flow immunoassay for detecting Yersinia pestis

D Hau, B Wade, C Lovejoy, SG Pandit… - PLoS Neglected …, 2022 - journals.plos.org
Background Yersinia pestis is the causative agent of plague, a zoonosis associated with
small mammals. Plague is a severe disease, especially in the pneumonic and septicemic …

[HTML][HTML] Extensive antibody cross-reactivity among infectious gram-negative bacteria revealed by proteome microarray analysis

SL Keasey, KE Schmid, MS Lee, J Meegan… - Molecular & Cellular …, 2009 - Elsevier
Antibodies provide a sensitive indicator of proteins displayed by bacteria during sepsis.
Because signals produced by infection are naturally amplified during the antibody response …

[HTML][HTML] Systematic analysis, identification, and use of CRISPR/Cas13a–associated crRNAs for sensitive and specific detection of the lcrV gene of Yersinia pestis

Z Schultzhaus, Z Wang, D Stenger - Diagnostic Microbiology and Infectious …, 2021 - Elsevier
CRISPR-associated proteins that produce a signal in the presence of a target nucleic acid
represent potentially powerful tools for diagnostics, but they also exhibit shortfalls that …

Next generation agents (synthetic agents): Emerging threats and challenges in detection, protection, and decontamination

A Sharma, G Gupta, T Ahmad, K Krishan… - Handbook on biological …, 2020 - Elsevier
Biological weapons are highly contagious in nature, designed for warfare scenarios, and
cause mass destruction by hammering the economic, environmental, and societal attributes …