Immune evasion and provocation by Mycobacterium tuberculosis

P Chandra, SJ Grigsby, JA Philips - Nature Reviews Microbiology, 2022 - nature.com
Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for
millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host …

Targeting memory T cell metabolism to improve immunity

M Corrado, EL Pearce - The Journal of clinical investigation, 2022 - jci.org
Vaccination affords protection from disease by activating pathogen-specific immune cells
and facilitating the development of persistent immunologic memory toward the vaccine …

Immunophenoty** assessment in a COVID-19 cohort (IMPACC): a prospective longitudinal study

IMPACC Manuscript Writing Team… - Science …, 2021 - science.org
The Immunophenoty** Assessment in a COVID-19 Cohort (IMPACC) is a prospective
longitudinal study designed to enroll 1000 hospitalized patients with COVID-19 …

Metabolomics of infectious diseases in the era of personalized medicine

M Rahman, HE Schellhorn - Frontiers in molecular biosciences, 2023 - frontiersin.org
Infectious diseases continue to be a major cause of morbidity and mortality worldwide.
Diseases cause perturbation of the host's immune system provoking a response that …

Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation

FC Ceballos, A Virseda-Berdices, S Resino… - Frontiers in …, 2022 - frontiersin.org
Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …

Plasma metabolomic alterations induced by COVID-19 vaccination reveal putative biomarkers reflecting the immune response

I Dagla, A Iliou, D Benaki, E Gikas, E Mikros… - Cells, 2022 - mdpi.com
Vaccination is currently the most effective strategy for the mitigation of the COVID-19
pandemic. mRNA vaccines trigger the immune system to produce neutralizing antibodies …

Transcriptionally active nasopharyngeal commensals and opportunistic microbial dynamics define mild symptoms in the COVID 19 vaccination breakthroughs

P Devi, P Kumari, A Yadav, B Tarai, S Budhiraja… - PLoS …, 2023 - journals.plos.org
The development of COVID 19 vaccines as an effort to mitigate the outbreak, has saved
millions of lives globally. However, vaccination breakthroughs have continuously challenged …

Bacille Calmette-Guérin vaccine reprograms human neonatal lipid metabolism in vivo and in vitro

J Diray-Arce, A Angelidou, KJ Jensen, MG Conti… - Cell reports, 2022 - cell.com
Vaccines have generally been developed with limited insight into their molecular impact.
While systems vaccinology enables characterization of mechanisms of action, these tools …

Quantitative LC–MS study of compounds found predictive of COVID-19 severity and outcome

I Roberts, M Wright Muelas, JM Taylor, AS Davison… - Metabolomics, 2023 - Springer
Introduction Since the beginning of the SARS-CoV-2 pandemic in December 2019 multiple
metabolomics studies have proposed predictive biomarkers of infection severity and …