Although many studies have examined quantitative trait variation across many species, only
a small number of genes and thereby molecular mechanisms have been discovered …

Over the last 20 years, studies of Caenorhabditis elegans natural diversity have
demonstrated the power of quantitative genetic approaches to reveal the evolutionary …

INTRODUCTION Genetic interactions occur when mutations in two or more genes combine
to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic …

Understanding how numerous quantitative trait loci (QTL) shape phenotypic variation is an
important question in genetics. To address this, we established a permanent population of …

INTRODUCTION Genetic interactions occur when mutations in different genes combine to
result in a phenotype that is different from expectation based on those of the individual …

Heritable variation in gene expression forms a crucial bridge between genomic variation
and the biology of many traits. However, most expression quantitative trait loci (eQTLs) …

INTRODUCTION Genetic interactions are identified when variants in different genes
combine to generate an unusual phenotype compared with the expected combined effect of …

Providing access to quantitative genomic data is key to ensure large-scale data validation
and promote new discoveries. TheCellMap. org serves as a central repository for storing and …

Epistasis between mutations can make adaptation contingent on evolutionary history. Yet
despite widespread 'microscopic'epistasis between the mutations involved, microbial …

Map** the genetic basis of complex traits is critical to uncovering the biological
mechanisms that underlie disease and other phenotypes. Genome-wide association studies …