Heterocyclic compounds have gained a lot of attention because of their numerous significant
medical and biological uses. Research interest on heterocyclic compounds is rapidly …

Abstract Carbonic anhydrase (CA, EC 4.2. 1.1) is an enzyme and a very omnipresent zinc
metalloenzyme which catalyzed the reversible hydration and dehydration of carbon dioxide …

The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

Abstract Sulfur-containing pyrroles (1–3), tris (2-pyridyl) phosphine (selenide) sulfide (4–5)
and 4-benzyl-6-(thiophen-2-yl) pyrimidin-2-amine (6) were synthesized and characterized …

Hemiindigoids comprise a range of natural and synthetic scaffolds that share the same
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …

New piperazine–chalcone hybrids and related pyrazoline derivatives have been designed
and synthesised as potential vascular endothelial growth factor receptor-2 (VEGFR-2) …

Abstract Starting from the compound (3, 4-dimethoxyphenyl)(2-(3, 4-dimethoxyphenyl)
cyclopent-1-en-1-yl) methanone (4), two diols and three tetrol derivatives were synthesised …

Carbonic anhydrases isoforms CA IX, and XII are known to be highly expressed in various
human tissues and malignancies. CA IX is a prominent target for especially colorectal …

Piperazine moiety is a cyclic molecule containing two nitrogen atoms in positions 1 and 4, as
well as four carbon atoms. Piperazine is one of the most sought heterocyclics for the …

Isoxazoles and isoxazolines are five-membered heterocyclic molecules containing nitrogen
and oxygen. Isoxazole and isoxazoline are the most popular heterocyclic compounds for …