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A basic review on estrogen receptor signaling pathways in breast cancer
L Clusan, F Ferrière, G Flouriot, F Pakdel - International journal of …, 2023 - mdpi.com
Breast cancer is the most common cancer and the deadliest among women worldwide.
Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen …
Estrogen signaling is closely associated with hormone-dependent breast cancer (estrogen …
Transcriptional control of energy metabolism by nuclear receptors
Transcriptional regulation of catabolic pathways is a central mechanism by which cells
respond to physiological cues to generate the energy required for anabolic pathways …
respond to physiological cues to generate the energy required for anabolic pathways …
Estrogen effects on cognitive and synaptic health over the lifecourse
Estrogen facilitates higher cognitive functions by exerting effects on brain regions such as
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …
An overview on Estrogen receptors signaling and its ligands in breast cancer
Estrogen governs the regulations of various pathological and physiological actions
throughout the body in both males and females. Generally, 17β-estradiol an endogenous …
throughout the body in both males and females. Generally, 17β-estradiol an endogenous …
Insufficient antibody validation challenges oestrogen receptor beta research
The discovery of oestrogen receptor β (ERβ/ESR2) was a landmark discovery. Its reported
expression and homology with breast cancer pharmacological target ERα (ESR1) raised …
expression and homology with breast cancer pharmacological target ERα (ESR1) raised …
Androgen receptor in prostate cancer
CA Heinlein, C Chang - Endocrine reviews, 2004 - academic.oup.com
The normal development and maintenance of the prostate is dependent on androgen acting
through the androgen receptor (AR). AR remains important in the development and …
through the androgen receptor (AR). AR remains important in the development and …
Physiological and molecular basis of thyroid hormone action
Thyroid hormones (THs) play critical roles in the differentiation, growth, metabolism, and
physiological function of virtually all tissues. TH binds to receptors that are ligand …
physiological function of virtually all tissues. TH binds to receptors that are ligand …
Molecular determinants of resistance to antiandrogen therapy
Using microarray-based profiling of isogenic prostate cancer xenograft models, we found
that a modest increase in androgen receptor mRNA was the only change consistently …
that a modest increase in androgen receptor mRNA was the only change consistently …
Mechanisms of estrogen action
S Nilsson, S Makela, E Treuter… - Physiological …, 2001 - journals.physiology.org
Our appreciation of the physiological functions of estrogens and the mechanisms through
which estrogens bring about these functions has changed during the past decade. Just as …
which estrogens bring about these functions has changed during the past decade. Just as …
Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes
L Björnström, M Sjöberg - Molecular endocrinology, 2005 - academic.oup.com
Estrogen receptors (ERs) act by regulating transcriptional processes. The classical
mechanism of ER action involves estrogen binding to receptors in the nucleus, after which …
mechanism of ER action involves estrogen binding to receptors in the nucleus, after which …