Beyond ligand binding: Single molecule observation reveals how riboswitches integrate multiple signals to balance bacterial gene regulation

A Chauvier, NG Walter - Current Opinion in Structural Biology, 2024 - Elsevier
Riboswitches are specialized RNA structures that orchestrate gene expression in response
to sensing specific metabolite or ion ligands, mostly in bacteria. Upon ligand binding, these …

Bacterial Rps3 counters oxidative and UV stress by recognizing and processing AP-sites on mRNA via a novel mechanism

M Afsar, A Shukla, F Ali, RK Maurya… - Nucleic Acids …, 2024 - academic.oup.com
Lesions and stable secondary structures in mRNA severely impact the translation efficiency,
causing ribosome stalling and collisions. Prokaryotic ribosomal proteins Rps3, Rps4 and …