[HTML][HTML] Targeting neuroinflammation in distal symmetrical polyneuropathy in diabetes

ZZ Chong, DL Menkes, N Souayah - Drug discovery today, 2024 - Elsevier
Diabetic distal symmetric polyneuropathy is the most common type of peripheral neuropathy
complication of diabetes mellitus. Neuroinflammation is emerging as an important …

[HTML][HTML] Trabecular bone score (TBS) in individuals with type 2 diabetes mellitus: an updated review

AI Trandafir, OC Sima, AM Gheorghe, A Ciuche… - Journal of clinical …, 2023 - mdpi.com
Bone fragility is a complication of type 2 diabetes mellitus (T2DM) that has been identified in
recent decades. Trabecular bone score (TBS) appears to be more accurate than bone …

[HTML][HTML] SGLT2 inhibitors in the treatment of diabetic kidney disease: more than just glucose regulation

J Klen, V Dolžan - Pharmaceutics, 2023 - mdpi.com
Diabetic kidney disease (DKD) is a severe and common complication and affects a quarter
of patients with type 2 diabetes mellitus (T2DM). Oxidative stress and inflammation related to …

Oxidative Stress, Endothelial Dysfunction, and N-Acetylcysteine in Type 2 Diabetes Mellitus

X Li, J Zou, A Lin, J Chi, H Hao, H Chen… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Cardiovascular diseases (CVDs) remain the leading cause of morbidity and
mortality globally. Endothelial dysfunction is closely associated with the development and …

Controlling Nutritional Status (CONUT) score is a novel marker of type 2 diabetes mellitus and diabetic microvascular complications

G Aktas, TT Duman, B Atak Tel - Postgraduate Medicine, 2024 - Taylor & Francis
Objectives Type 2 diabetes mellitus (T2DM) and its microvascular complications are
characterized by chronic inflammation. The Controlling Nutritional Status (CONUT) score is …

Machine learning and molecular dynamics simulations predict potential TGR5 agonists for type 2 diabetes treatment

OA Enejoh, CH Okonkwo, H Nortey, OA Kemiki… - Frontiers in …, 2025 - frontiersin.org
Introduction Treatment of type 2 diabetes (T2D) remains a significant challenge because of
its multifactorial nature and complex metabolic pathways. There is growing interest in finding …

[PDF][PDF] Navigating the frontier: emerging techniques for detecting microvascular complications in type 2 diabetes mellitus: a comprehensive review

SS Raut, S Acharya, V Deolikar, S Mahajan - Cureus, 2024 - cureus.com
This review comprehensively explores emerging techniques for detecting microvascular
complications in Type 2 Diabetes Mellitus (T2DM), addressing the critical need for …

[HTML][HTML] Silk Fibroin Nanofibers: Advancements in Bioactive Dressings through Electrospinning Technology for Diabetic Wound Healing

A Aldahish, N Shanmugasundaram, R Vasudevan… - Pharmaceuticals, 2024 - mdpi.com
Background: Non-healing diabetic wounds represent a significant clinical challenge
globally, necessitating innovative approaches in drug delivery to enhance wound healing …

Glucosamine substituted sulfonylureas: IRS–PI3K–PKC–AKT–GLUT4 insulin signalling pathway intriguing agent

GARY Suaifan, B Alkhawaja, MB Shehadeh… - RSC Medicinal …, 2024 - pubs.rsc.org
Normally, skeletal muscle accounts for 70–80% of insulin-stimulated glucose uptake in the
postprandial hyperglycemia state. Consequently, abnormalities in glucose uptake by …

[HTML][HTML] Exploring the promising impacts of naringin and its aglycone constituent naringenin as major citrus flavonoids on diabetes and its complications

S Fotouhi, A Yavari, AR Bagheri, VR Askari… - Journal of Functional …, 2025 - Elsevier
Due to their capacity to fight apoptosis, inflammation, and oxidative stress, naringin and its
aglycone naringenin are considered valuable therapeutic agents for diabetes mellitus (DM) …