Global brain inflammation in stroke
Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal
cell death and the release of factors such as damage-associated molecular patterns …
cell death and the release of factors such as damage-associated molecular patterns …
The potential impact of neuroimaging and translational research on the clinical management of lacunar stroke
Lacunar infarcts represent one of the most frequent subtypes of ischemic strokes and may
represent the first recognizable manifestation of a progressive disease of the small …
represent the first recognizable manifestation of a progressive disease of the small …
Cognitive impairment and dementia after stroke: design and rationale for the DISCOVERY study
Stroke is a leading cause of the adult disability epidemic in the United States, with a major
contribution from poststroke cognitive impairment and dementia (PSCID), the rates of which …
contribution from poststroke cognitive impairment and dementia (PSCID), the rates of which …
Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke
CC Esenwa, MS Elkind - Nature Reviews Neurology, 2016 - nature.com
Proinflammatory conditions, including acute and chronic infections, have been associated
with an increased risk of stroke. The risk of stroke is increased by both the acute and chronic …
with an increased risk of stroke. The risk of stroke is increased by both the acute and chronic …
The role of genetic polymorphism and other factors on clopidogrel resistance (CR) in an Asian population with coronary heart disease (CHD)
Clopidogrel is a widely-used antiplatelet drug. It is important for the treatment and prevention
of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore …
of coronary heart disease. Clopidogrel can effectively reduce platelet activity and therefore …
Blood biomarkers for stroke diagnosis and management
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
C-Reactive Protein, Interleukin-6, and Vascular Recurrence According to Stroke Subtype: An Individual Participant Data Meta-Analysis
Background and Objectives Anti-inflammatory therapies reduce major adverse
cardiovascular events (MACE) in coronary artery disease but remain unproven after stroke …
cardiovascular events (MACE) in coronary artery disease but remain unproven after stroke …
Interleukin-6, C-reactive protein, fibrinogen, and risk of recurrence after ischaemic stroke: systematic review and meta-analysis
JJ McCabe, E O'reilly, S Coveney… - European stroke …, 2021 - journals.sagepub.com
Background Recent randomised trials showed benefit for anti-inflammatory therapies in
coronary disease but excluded stroke. The prognostic value of blood inflammatory markers …
coronary disease but excluded stroke. The prognostic value of blood inflammatory markers …
An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury
Chronic systemic sterile inflammation is implicated in the pathogenesis of cerebrovascular
disease and white matter injury. Non-invasive blood markers for risk stratification and …
disease and white matter injury. Non-invasive blood markers for risk stratification and …
High-sensitive C-reactive protein predicts recurrent stroke and poor functional outcome: subanalysis of the clopidogrel in high-risk patients with acute nondisabling …
Background and Purpose—Minor stroke and transient ischemic attack are common
disorders with high rate of subsequent disabling stroke. We aim to investigate the role of …
disorders with high rate of subsequent disabling stroke. We aim to investigate the role of …