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Identity by descent: variation in meiosis, across genomes, and in populations
EA Thompson - Genetics, 2013 - academic.oup.com
Gene identity by descent (IBD) is a fundamental concept that underlies genetically mediated
similarities among relatives. Gene IBD is traced through ancestral meioses and is defined …
similarities among relatives. Gene IBD is traced through ancestral meioses and is defined …
Linkage disequilibrium and association studies in higher plants: present status and future prospects
During the last two decades, DNA-based molecular markers have been extensively utilized
for a variety of studies in both plant and animal systems. One of the major uses of these …
for a variety of studies in both plant and animal systems. One of the major uses of these …
Score tests for association between traits and haplotypes when linkage phase is ambiguous
A key step toward the discovery of a gene related to a trait is the finding of an association
between the trait and one or more haplotypes. Haplotype analyses can also provide critical …
between the trait and one or more haplotypes. Haplotype analyses can also provide critical …
Association study designs for complex diseases
Assessing the association between DNA variants and disease has been used widely to
identify regions of the genome and candidate genes that contribute to disease. However …
identify regions of the genome and candidate genes that contribute to disease. However …
Genomewide association studies: history, rationale, and prospects for psychiatric disorders
Psychiatric GWAS Consortium … - American Journal of …, 2009 - psychiatryonline.org
Objective: The authors conducted a review of the history and empirical basis of genomewide
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …
association studies (GWAS), the rationale for GWAS of psychiatric disorders, results to date …
Haplotypes vs single marker linkage disequilibrium tests: what do we gain?
J Akey, L **, M ** complex traits
Geneticists have repeatedly turned to population isolates for map** and cloning
Mendelian disease genes. Population isolates possess many advantages in this regard …
Mendelian disease genes. Population isolates possess many advantages in this regard …
The genetics of phenylthiocarbamide perception
SW Guo, DR Reed - Annals of human biology, 2001 - Taylor & Francis
The ability to taste the bitter compound phenylthiocarbamide (PTC) and related chemicals is
bimodal, and all human populations tested to date contain some people who can and some …
bimodal, and all human populations tested to date contain some people who can and some …
[KNYGA][B] Genetic Resources, Chromosome Engineering, and Crop Improvement: Cereals, Volume 2
RJ Singh, PP Jauhar - 2006 - taylorfrancis.com
Summarizing landmark research, Volume 2 of this essential series furnishes information on
the availability of germplasm resources that breeders can exploit for producing high-yielding …
the availability of germplasm resources that breeders can exploit for producing high-yielding …
Linkage disequilibrium and the search for complex disease genes
LB Jorde - Genome research, 2000 - genome.cshlp.org
During the past two decades, linkage analysis has been phenomenally successful in
localizing Mendelian disease genes. Linkage disequilibrium (LD) analysis, which effectively …
localizing Mendelian disease genes. Linkage disequilibrium (LD) analysis, which effectively …