The discovery of numerous noncoding RNA (ncRNA) transcripts in species from yeast to
mammals has dramatically altered our understanding of cell biology, especially the biology …

DNA methylation is a crucial epigenetic modification of the genome that is involved in
regulating many cellular processes. These include embryonic development, transcription …

Long noncoding RNAs (lncRNAs) have gained widespread attention in recent years as a
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …

Since its discovery in 1983, the epigenetics of human cancer has been in the shadows of
human cancer genetics. But this area has become increasingly visible with a growing …

Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …

Recent studies have demonstrated that transplanted bone marrow cells can turn into
unexpected lineages including myocytes, hepatocytes, neurons and many others. A …

Epigenetics is the study of heritable changes in gene expression that occur without a
change in DNA sequence. Epigenetic phenomena have major economic and medical …

Recent data in humans and animals suggest that assisted reproductive technology (ART)
might affect the epigenetics of early embryogenesis and might cause birth defects. We report …

The identification of ultraconserved noncoding sequences in vertebrates has been
associated with developmental regulators and DNA-binding proteins. One of the first of …

Over the past decade there has been a greater understanding of genomic complexity in
eukaryotes ushered in by the immense technological advances in high-throughput …