Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

E Schneider, KJ O'Riordan, G Clarke, JF Cryan - Nature metabolism, 2024 - nature.com
The prevalence of brain disorders, including stress-related neuropsychiatric disorders and
conditions with cognitive dysfunction, is rising. Poor dietary habits contribute substantially to …

Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Early-life differences in the gut microbiota composition and functionality of infants at elevated likelihood of develo** autism spectrum disorder

S Zuffa, P Schimmel, A Gonzalez-Santana… - Translational …, 2023 - nature.com
Evidence from cross-sectional human studies, and preliminary microbial-based intervention
studies, have implicated the microbiota-gut-brain axis in the neurobiology of autism …

Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Sex shapes gut–microbiota–brain communication and disease

KC Hokanson, C Hernández, GE Deitzler… - Trends in …, 2024 - cell.com
Research into the microbiota–gut–brain axis (MGBA) has entered a golden age, raising the
hope that therapeutics acting on it may offer breakthroughs in the treatment of many …

[HTML][HTML] A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis

JS Boles, ME Krueger, JE Jernigan, CL Cole… - Brain, Behavior, and …, 2024 - Elsevier
The gut and brain are increasingly linked in human disease, with neuropsychiatric
conditions classically attributed to the brain showing an involvement of the intestine and …

Autism spectrum disorders and the gastrointestinal tract: insights into mechanisms and clinical relevance

LY Hung, KG Margolis - Nature Reviews Gastroenterology & …, 2024 - nature.com
Autism spectrum disorders (ASDs) are recognized as central neurodevelopmental disorders
diagnosed by impairments in social interactions, communication and repetitive behaviours …

Antibiotic-perturbed microbiota and the role of probiotics

H Szajewska, KP Scott, T de Meij… - Nature Reviews …, 2024 - nature.com
The disruptive effect of antibiotics on the composition and function of the human microbiota
is well established. However, the hypothesis that probiotics can help restore the antibiotic …

Large-scale metagenomic analysis of oral microbiomes reveals markers for autism spectrum disorders

P Manghi, M Filosi, M Zolfo, LG Casten… - Nature …, 2024 - nature.com
The link between the oral microbiome and neurodevelopmental disorders remains a
compelling hypothesis, still requiring confirmation in large-scale datasets. Leveraging over …

Harnessing human microbiomes for disease prediction

Y Liu, M Fachrul, M Inouye, G Méric - Trends in microbiology, 2024 - cell.com
The human microbiome has been increasingly recognized as having potential use for
disease prediction. Predicting the risk, progression, and severity of diseases holds promise …