Glioblastoma (GBM), the predominant and primary malignant intracranial tumor, poses a
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …

Cardiovascular disease (CVD) is the primary global cause of death, and inflammation is a
crucial factor in the development of CVDs. The acute phase inflammatory protein pentraxin 3 …

Background The recent development of dendritic cell (DC)‐based immunotherapy has
resulted in advances in glioblastoma multiforme (GBM) treatment. However, the cell fate of …

A spectrum of immune states resulting from tumor resident macrophages and T-lymphocytes
in the solid tumor microenvironment correlates with patient outcomes. We hypothesized that …

Although cancer can be cured if detected early and treated effectively, it is still a leading
cause of death worldwide. Tumor development can be limited by an appropiate immune …

Germ cell tumors (GCT) are the most common solid tumors in young men of age 15-40. In
previous studies, we profiled the interaction of GCT cells with cells of the tumor …

Cancer has become a leading cause of death and disease burden worldwide, closely
related to rapid socioeconomic development. However, the fundamental reason is the lack …

Background This study aimed to investigate the effect and mechanism of Pentraxin 3 (PTX3)
on myocardial injury in sepsis. Methods Thirty male C57BL/6 mice were randomly assigned …

Introduction The most prevalent bone tumor with a relatively high level of aggressiveness
and malignancy is osteosarcoma. The characteristics of the serpin family in osteosarcoma …

Backgrounds Hepatic ischemia–reperfusion injury (IRI) triggers macrophage activation,
which in turn mediates inflammatory responses and affects tissue repair and injury severity …