Reelin was originally identified as a regulator of neuronal migration and synaptic function,
but its non-neuronal functions have received far less attention. Reelin participates in organ …

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized
by difficulties in social interaction, language development delays, repeated body …

Alternative splicing (AS) generates vast transcriptomic and proteomic complexity. However,
which of the myriad of detected AS events provide important biological functions is not well …

Importance Neuroticism is a pervasive risk factor for psychiatric conditions. It genetically
overlaps with major depressive disorder (MDD) and is therefore an important phenotype for …

We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …

Reelin is a glycoprotein that serves important roles both during development (regulation of
neuronal migration and brain lamination) and in adulthood (maintenance of synaptic …

Proper neuronal migration and laminar formation during corticogenesis is essential for
normal brain function. Disruption of these developmental processes is thought to be …

Extraversion is a relatively stable and heritable personality trait associated with numerous
psychosocial, lifestyle and health outcomes. Despite its substantial heritability, no genetic …

Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Autism spectrum disorders (ASD) are neurodevelopmental disorders typically diagnosed in
childhood, characterized by core social dysfunction, rigid and repetitive behaviors, restricted …