Investigating One Health risks for human colonisation with extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Malawian …

D Cocker, K Chidziwisano, M Mphasa… - The Lancet …, 2023 - thelancet.com
Background Low-income countries have high morbidity and mortality from drug-resistant
infections, especially from enteric bacteria such as Escherichia coli. In these settings …

Risk Factors, Temporal Dependence, and Seasonality of Human Extended-Spectrum β-Lactamases-Producing Escherichia coli and Klebsiella pneumoniae …

M Sammarro, B Rowlingson, D Cocker… - Clinical Infectious …, 2023 - academic.oup.com
Abstract Background Sub-Saharan Africa has the highest estimated death rate attributable to
antimicrobial resistance, especially from extended-spectrum β-lactamase-producing …

Time to define One Health approaches to tackling antimicrobial resistance

P Musicha, T Morse, D Cocker, L Mugisha… - nature …, 2024 - nature.com
Recent data re-affirm antimicrobial resistance (AMR) as a One Health problem, particularly
in low-and middle-income countries. Transdisciplinary and intersectoral collaboration are …

Inference on extended-spectrum beta-lactamase Escherichia coli and Klebsiella pneumoniae data through SMC2

L Rimella, S Alderton, M Sammarro… - Journal of the Royal …, 2023 - academic.oup.com
We propose a novel stochastic model for the spread of antimicrobial-resistant bacteria in a
population, together with an efficient algorithm for fitting such a model to sample data. We …

One Health in Eastern Africa: No barriers for ESBL producing E. coli transmission or independent antimicrobial resistance gene flow across ecological compartments

P Musicha, MA Beale, D Cocker, FA Oruru, A Zuza… - bioRxiv, 2024 - biorxiv.org
The One Health paradigm considers the interdependence of human, animal and
environmental health. In high-income countries, limited evidence has been found from …

Approximating optimal SMC proposal distributions in individual-based epidemic models

L Rimella, C Jewell, P Fearnhead - arxiv preprint arxiv:2206.05161, 2022 - arxiv.org
Many epidemic models are naturally defined as individual-based models: where we track
the state of each individual within a susceptible population. Inference for individual-based …

Investigating risks for human colonisation with extended spectrum beta-lactamase producing E. coli and K. pneumoniae in Malawian households: a one health …

D Cocker, K Chidziwisano, M Mphasa, T Mwapasa… - medRxiv, 2022 - medrxiv.org
Background Low-and middle-income countries (LMICs) have high morbidity and mortality
from drug-resistant infections, especially from enteric bacteria such as Escherichia coli …

Risk perception and psychosocial factors influencing exposure to antimicrobial resistance through environmental pathways in Malawi

K Chidziwisano, D Cocker… - American Journal of …, 2024 - pureportal.strath.ac.uk
Antimicrobial-resistant (AMR) bacteria are prevalent in household and environmental
settings in low-income locations. However, there are limited data on individuals' …

Scalable calibration for partially observed individual-based epidemic models through categorical approximations

L Rimella, N Whiteley, C Jewell, P Fearnhead… - arxiv preprint arxiv …, 2025 - arxiv.org
The computational cost of exact likelihood evaluation for partially observed and highly-
heterogeneous individual-based models grows exponentially with the population size …

[PDF][PDF] Prevalence and characteristics of intestinal carriage of multidrug-resistant enterobacteriaceae in outpatients in abidjan

KKA Adams, KK Stéphane, YI Alexia… - American Journal of …, 2024 - researchgate.net
Background: The growing threat of antibiotic resistance poses a major challenge to global
public health as it could lead to up to 10 million deaths annually by 2050, particularly in low …