Fluorescence microscopy provides an efficient and unique approach to study fixed and
living cells because of its versatility, specificity, and high sensitivity. Fluorescence …

The'invisible hand'is a term originally coined by Adam Smith in The Theory of Moral
Sentiments to describe the forces of self-interest, competition and supply and demand that …

Somlyo, Andrew P., and Avril V. Somlyo. Ca2+ Sensitivity of Smooth Muscle and Nonmuscle
Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase. Physiol Rev 83 …

The current advances in fluorescence microscopy, coupled with the development of new
fluorescent probes, make fluorescence resonance energy transfer (FRET) a powerful …

Abstract The GTPases Rac1, RhoA and Cdc42 act together to control cytoskeleton
dynamics,,. Recent biosensor studies have shown that all three GTPases are activated at the …

Peripheral nerves injuries result in paralysis, anesthesia and lack of autonomic control of the
affected body areas. After injury, axons distal to the lesion are disconnected from the …

Focal adhesions undergo myosin-II-mediated maturation wherein they grow and change
composition to modulate integrin signalling for cell migration, growth and differentiation. To …

Rho GTPases play an essential role in regulating cell spreading, adhesion, and migration
downstream of integrin engagement with the extracellular matrix. In this review, we focus on …

The p21 Rho-family of small GTPases are master regulators of actin cytoskeleton
rearrangements. Their functions have been well characterized in terms of their effects toward …

Our brain serves as a center for cognitive function and neurons within the brain relay and
store information about our surroundings and experiences. Modulation of this complex …