Galectin-9 alleviates LPS-induced preeclampsia-like impairment in rats via switching decidual macrophage polarization to M2 subtype

ZH Li, LL Wang, H Liu, KP Muyayalo… - Frontiers in …, 2019 - frontiersin.org
Dysfunction of decidual macrophages (DMs) is considered a critical event in the
pathogenesis of pre-eclampsia (PE). T cell immunoglobulin mucin 3 (Tim-3) is an important …

The PD-1/PD-L1 inhibitory pathway is altered in pre-eclampsia and regulates T cell responses in pre-eclamptic rats

M Tian, Y Zhang, Z Liu, G Sun, G Mor, A Liao - Scientific reports, 2016 - nature.com
The programmed cell death-1 (PD-1)/PD-ligand 1 (PD-L1) pathway is critical to immune
homeostasis by promoting regulatory T (Treg) development and inhibiting effector T (such as …

A Combined Supplementation of Omega-3 Fatty Acids and Micronutrients (Folic Acid, Vitamin B12) Reduces Oxidative Stress Markers in a Rat Model of Pregnancy …

NG Kemse, AA Kale, SR Joshi - PloS one, 2014 - journals.plos.org
Objectives Our earlier studies have highlighted that an altered one carbon metabolism
(vitamin B12, folic acid, and docosahexaenoic acid) is associated with preeclampsia …

[HTML][HTML] Ghrelin alleviates placental dysfunction by down-regulating NF-κB phosphorylation in LPS-induced rat model of preeclampsia

J Shen, N Hu, Z Wang, L Yang, R Chen, L Zhang… - European Journal of …, 2024 - Elsevier
In our previous study, we uncovered that ghrelin promotes angiogenesis in human umbilical
vein endothelial cells (HUVECs) in vitro by activating the Jagged1/Notch2/VEGF pathway in …

Açaí (Euterpe oleracea Mart) seed extract protects against maternal vascular dysfunction, hypertension, and fetal growth restriction in experimental preeclampsia

AS da Silva, DVQ Nunes, LCRM Carvalho… - Hypertension in …, 2020 - Taylor & Francis
ABSTRACT Objective To investigate whether Euterpe oleracea Mart.(açaí) seed extract
(ASE) prevents maternal cardiovascular changes and intrauterine growth restriction (IUGR) …

[PDF][PDF] Ethanolic extract of Moringa oleifera leaves improve inflammation, angiogenesis, and blood pressure in rat model of preeclampsia

A Batmomolin, A Ahsan, IWA Wiyasa… - Journal of Applied …, 2020 - japsonline.com
The aim of this study is to investigate the effect of the ethanolic extract of Moringa oleifera
leaves (EMOL) to improve inflammation, angiogenesis, and blood pressure by evaluating …

Simvastatin alleviates pathology in a rat model of preeclampsia involving ERK/MAPK pathway

X Dong, D Shi - Reproductive Sciences, 2017 - journals.sagepub.com
Preeclampsia (PE) is a pregnancy-specific condition characterized by new-onset
hypertension. There is evidence suggesting that imbalances of angiogenic factors, oxidative …

Combining curcumin and aspirin ameliorates preeclampsia‐like symptoms by inhibiting the placental TLR4/NF‐κB signaling pathway in rats

Y Ju, Y Feng, Y Yang, X Hou, X Zhang… - Journal of Obstetrics …, 2023 - Wiley Online Library
Aim Preeclampsia (PE) is a common medical complication of pregnancy characterized by
high blood pressure and proteinuria after the 20th gestational week. This study aimed to …

Hydroxychloroquine reduces hypertension and soluble fms-like kinase-1 in a Nω-nitro-l-arginine methyl ester-induced preeclampsia rat model

M Choi, JR Hwang, JH Sung, N Byun… - Journal of …, 2022 - journals.lww.com
Objective: Hydroxychloroquine, a drug used for malaria and autoimmune diseases
reportedly has beneficial effects against preeclampsia in pregnant women with lupus …

Protection of Pacific white shrimp (Penaeus vannamei) against white spot syndrome virus infection by nitric oxide-generating compound S-nitrosoglutathione

Q Lai, C Yu, F Zhao, Y Cheng, Q Zheng, C Pan, ZY Lin… - Aquaculture, 2024 - Elsevier
Nitric oxide (NO), a highly reactive free radical generated endogenously by nitric oxide
synthase (NOS), plays crucial roles in immune defense against a broad range of pathogens …