Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Experimental efforts to understand how the brain represents, stores and processes
information require high-fidelity recordings of multiple different forms of neural activity within …

Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

We have produced gene expression profiles of all 302 neurons of the C. elegans nervous
system that match the single-cell resolution of its anatomy and wiring diagram. Our results …

Establishing how neural function emerges from network properties is a fundamental problem
in neuroscience. Here, to better understand the relationship between the structure and the …

Cognitive neuroscience studies in humans have enabled decades of impactful discoveries
but have primarily been limited to recording the brain activity of immobile participants in a …

Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …

Light-field microscopy has emerged as a technique of choice for high-speed volumetric
imaging of fast biological processes. However, artifacts, nonuniform resolution and a slow …

Comprehensively resolving neuronal identities in whole-brain images is a major challenge.
We achieve this in C. elegans by engineering a multicolor transgene called NeuroPAL (a …